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Article
Evolution and function of residual solvent in polymer-Li2B12H12 composite solid electrolyte
Composite solid electrolytes (CSEs) containing polymer matrices and inorganic fillers hold promise for the next generation of solid-state batteries. However, the role of residual solvents in CSEs remains contr...
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Article
Influence of Heat-setting Temperature on the Microporous Structure and Properties of PP/HDPE Bilayer Microporous Membranes
Due to the mechanical stability of PP layer, the PP/HDPE double-layer microporous membrane could be prepared at a higher heat-setting temperature than that of PE monolayer membrane. In this work, the effects o...
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Article
Open AccessPJA1-mediated suppression of pyroptosis as a driver of docetaxel resistance in nasopharyngeal carcinoma
Chemoresistance is a main reason for treatment failure in patients with nasopharyngeal carcinoma, but the exact regulatory mechanism underlying chemoresistance in nasopharyngeal carcinoma remains to be elucida...
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Article
Ultrahard X-ray multifunctional application beamline at the SSRF
The ultrahard X-ray multifunctional application beamline (BL12SW) is a phase-II beamline project at the Shanghai Synchrotron Radiation Facility. The primary X-ray techniques used at the beamline are high-energ...
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Article
A Dynamic Covalent Bonding-based Nanoplatform for Intracellular Co-Delivery of Protein Drugs and Chemotherapeutics with Enhanced Anti-Cancer Effect
Efficient intracellular delivery of protein drugs is critical for protein therapy. The combination of protein drugs with chemotherapeutics represents a promising strategy in enhancing anti-cancer effect. Howev...
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Article
Open AccessLong-term remission and survival in patients with relapsed or refractory multiple myeloma after treatment with LCAR-B38M CAR T cells: 5-year follow-up of the LEGEND-2 trial
The autologous anti–B-cell maturation antigen (BCMA) chimeric antigen receptor (CAR) T-cell therapy LCAR-B38M has been approved for the treatment of relapsed and refractory multiple myeloma in many countries a...
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Article
Open AccessRemnant cholesterol trajectory and subclinical arteriosclerosis: a 10-year longitudinal study of Chinese adults
We aimed to identify different trajectories of remnant cholesterol (RC) and investigate the association of RC trajectories with vascular endothelial function and atherosclerosis progression in a longitudinal c...
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Article
Open AccessOral arsenic plus imatinib versus imatinib solely for newly diagnosed chronic myeloid leukemia: a randomized phase 3 trial with 5-year outcomes
The synergistic effects of combining arsenic compounds with imatinib against chronic myeloid leukemia (CML) have been established using in vitro data. We conducted a clinical trial to compare the efficacy of t...
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Article
Redox mediator-stabilized wide-bandgap perovskites for monolithic perovskite-organic tandem solar cells
Halide segregation critically limits the stability of mixed-halide perovskite solar cells under device operational conditions. There is a strong indication that halide oxidation is the primary driving force be...
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Article
Open AccessCorrection: Seasonality of respiratory syncytial virus infection in children hospitalized with acute lower respiratory tract infections in Hunan, China, 2013–2022
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Article
Open AccessAssessing intra- and inter-molecular charge transfer excitations in non-fullerene acceptors using electroabsorption spectroscopy
Organic photovoltaic cells using Y6 non-fullerene acceptors have recently achieved high efficiency, and it was suggested to be attributed to the charge-transfer (CT) nature of the excitations in Y6 aggregates....
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Article
Open AccessSeasonality of respiratory syncytial virus infection in children hospitalized with acute lower respiratory tract infections in Hunan, China, 2013–2022
In China, respiratory syncytial virus (RSV) infections traditionally occur during the spring and winter seasons. However, a shift in the seasonal trend was noted in 2020–2022, during the coronavirus disease 20...
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Article
Open AccessRGA1 regulates grain size, rice quality and seed germination in the small and round grain mutant srg5
Generating elite rice varieties with high yield and superior quality is the main goal of rice breeding programs. Key agronomic traits, including grain size and seed germination characteristics, affect the fina...
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Article
Diagnosis, treatment and prevention of severe acute respiratory syndrome coronavirus 2 infection in children: experts’ consensus statement updated for the Omicron variant
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Article
Open AccessCorrection to: Expert consensus on the diagnosis, treatment, and prevention of respiratory syncytial virus infections in children
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Article
Open AccessRegulatory T cells use heparanase to access IL-2 bound to extracellular matrix in inflamed tissue
Although FOXP3+ regulatory T cells (Treg) depend on IL-2 produced by other cells for their survival and function, the levels of IL-2 in inflamed tissue are low, making it unclear how Treg access this critical res...
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Article
Open AccessUtilizing physician modified fenestration on the castor branched stent technique for reconstruction of an isolated left vertebral artery on the aortic arch
The study aimed to provide physician modified fenestration (PMF) on a single-branched stent for the aortic arch (Castor) to protect the isolated left vertebral artery (ILVA) during thoracic endovascular aortic...
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Article
Open AccessDecoding the complexity of on-target integration: characterizing DNA insertions at the CRISPR-Cas9 targeted locus using nanopore sequencing
CRISPR-Cas9 technology has advanced in vivo gene therapy for disorders like hemophilia A, notably through the successful targeted incorporation of the F8 gene into the Alb locus in hepatocytes, effectively cur...
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Article
Speciation analysis and toxicity evaluation of arsenolipids—an overview focusing on sea food
Arsenic, which can be divided into inorganic and organic arsenic, is a toxic metalloid that has been identified as a human carcinogen. A common source of arsenic exposure in seafood is arsenolipid, which is a ...
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Article
Medulla Tetrapanacis water extract alleviates inflammation and infection by regulating macrophage polarization through MAPK signaling pathway
Medulla Tetrapanacis (MT) is a commonly used herb to promote lactation and manage mastitis in lactating mothers. However, its anti-inflammatory and anti-bacterial effects are currently unknown. We hypothesized th...
