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  1. No Access

    Article

    Non-viral S/MAR vectors replicate episomally in vivo when provided with a selective advantage

    The ideal gene therapy vector should enable persistent expression without the limitations of safety and reproducibility. We previously reported that a prototype plasmid vector, containing a scaffold matrix att...

    S P Wong, O Argyros, C Coutelle, R P Harbottle in Gene Therapy (2011)

  2. No Access

    Article

    Persistent episomal transgene expression in liver following delivery of a scaffold/matrix attachment region containing non-viral vector

    An ideal gene therapy vector should enable persistent transgene expression without limitations of safety and reproducibility. Here we report the development of a non-viral episomal plasmid DNA (pDNA) vector th...

    O Argyros, S P Wong, M Niceta, S N Waddington, S J Howe, C Coutelle… in Gene Therapy (2008)