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Article
Volume dynamics in migrating epithelial cells measured with atomic force microscopy
Migration of transformed renal epithelial cells (transformed Madin-Darby canine kidney cells, MDCK-F cells) relies on the activity of a Ca2+-sensitive K+ channel (IK channel) that is more active at the rear end o...
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Article
Molecular weights of individual proteins correlate with molecular volumes measured by atomic force microscopy
Proteins are usually identified by their molecular weights, and atomic force microscopy (AFM) produces images of single molecules in three dimensions. We have used AFM to measure the molecular volumes of a nu...
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Article
Imaging excised apical plasma membrane patches of MDCK cells in physiological conditions with atomic force microscopy
We combined the patch-clamp technique with atomic force microscopy (AFM) to visualize plasma membrane proteins protruding from the extracellular surface of cultured kidney cells (MDCK cells). To achieve molec...