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Article
ATP-Induced Shape Change of Nuclear Pores Visualized with the Atomic Force Microscope
Bidirectional transport of molecules between nucleus and cytoplasm through the nuclear pore complexes (NPCs) spanning the nuclear envelope plays a fundamental role in cell function and metabolism. Nuclear imp...
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Article
Kiss and Run Mechanism in Exocytosis
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Article
Kiss and Run Mechanism in Exocytosis
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Article
Secretion Pores in Human Endothelial Cells during Acute Hypoxia
Weibel-Palade bodies (WPB) are endothelial vesicles that store von Willebrand factor (vWF), involved in the early phase of hemostasis. In the present study we investigated the morphodynamics of single WPB plas...
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Article
Endothelial Cell Swelling by Aldosterone
There is accumulating evidence that mineralocorticoids not only act on kidney but also on the cardiovascular system. We investigated the response of human umbilical venous endothelial cells (HUVECs) to aldoste...
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Article
Open AccessMss4 protein is a regulator of stress response and apoptosis
Mss4 (mammalian suppressor of Sec4) is an evolutionarily highly conserved protein and shows high sequence and structural similarity to nucleotide exchange factors. Although Mss4 tightly binds a series of exocy...