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  1. No Access

    Article

    Binding of Paroxetine to the Serotonin Transporter in Membranes from Different Cells, Subcellular Fractions and Species

    The binding of [3H]-paroxetine to membrane serotonin transporter (SERT) has been studied in membranes from different sources and subcellular fractions. From rat were membranes from venous blood platelets, brain t...

    A. Cupello, C. Albano, E. Gatta, S. Scarrone, E. Villa, G. Zona in Neurochemical Research (2009)

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    Article

    Successful Treatment of Epilepsy with Serotonin Reuptake Inhibitors: Proposed Mechanism

    The widely used antidepressants Specific Serotonin Reuptake Inhibitors (SSRI) have been tried with success as anticonvulsants in cases of nonsymptomatic epilepsy. This attempt was performed on the basis of exp...

    C. Albano, A. Cupello, P. Mainardi, S. Scarrone, E. Favale in Neurochemical Research (2006)

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    Article

    Ethanol Inhibits the Binding of Substance P to Rat Brain Cortex NK1 Receptors

    The binding of 125I-labeled substance P (SP) to rat brain cortex membranes has been studied Under control conditions and in the presence of ethanol. The binding of SP at low concentrations (20–1000 pM) gave two c...

    S. Scarrone, A. Cappelli, A. Cupello, M. Matarrese, R. M. Moresco… in Neurochemical Research (2003)

  4. No Access

    Article

    Pretreatment of Rat Brain Synaptosomes with GABA Increases Subsequent GABA Uptake Via GABAB Receptor Activation

    Pretreatment with 100 μM GABA of synaptosomes purified from rat brain results in an increased uptake of the labelled neurotransmitter in subsequent incubations. The effect is blocked by a GABAB receptor antagonis...

    A. Cupello, S. Scarrone in Neurochemical Research (2001)