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Article

Anti-leukemic activity and tolerability of anti-human CD47 monoclonal antibodies

CD47, a broadly expressed cell surface protein, inhibits cell phagocytosis via interaction with phagocyte-expressed SIRPα. A variety of hematological malignancies demonstrate elevated CD47 expression, suggesti...

E C Pietsch, J Dong, R Cardoso, X Zhang, D Chin, R Hawkins, T Dinh… in Blood Cancer Journal (2017)