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    Cell cycle arrest is sufficient for p53-mediated tumor regression

    p53 gene therapy can induce tumor regression, but the low efficacy of in vivo gene transfer has greatly hampered the mechanistic analysis of this antitumoral activity. We therefore used a p53-null human NSCLC cel...

    L Dubrez, J-L Coll, A Hurbin, F de Fraipont, S Lantejoul, M-C Favrot in Gene Therapy (2001)