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    A compartmentalized phosphoinositide signaling axis at cilia is regulated by INPP5E to maintain cilia and promote Sonic Hedgehog medulloblastoma

    Sonic Hedgehog (SHH) signaling at primary cilia drives the proliferation and progression of a subset of medulloblastomas, the most common malignant paediatric brain tumor. Severe side effects associated with c...

    S E Conduit, V Ramaswamy, M Remke, D N Watkins, B J Wainwright, M D Taylor… in Oncogene (2017)