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  1. No Access

    Article

    Expression of AML1-ETO in human myelomonocytic cells selectively inhibits granulocytic differentiation and promotes their self-renewal

    The t(8;21) translocation is one of the most frequent translocations in acute myeloid leukaemia (AML), giving rise to the AML1-ETO fusion protein (or RUNX1-CBF2T1). This abnormality is associated with myelocyt...

    A Tonks, A J Tonks, L Pearn, L Pearce, T Hoy, S Couzens, J Fisher, A K Burnett… in Leukemia (2004)

  2. No Access

    Article

    Harmonemia: a universal strategy for flow cytometry immunophenoty**—A European LeukemiaNet WP10 study

    F Lacombe, E Bernal, D Bloxham, S Couzens, M G D Porta, U Johansson, W Kern… in Leukemia (2016)

  3. No Access

    Article

    Expression of CD33 is a predictive factor for effect of gemtuzumab ozogamicin at different doses in adult acute myeloid leukaemia

    It remains unclear in adult acute myeloid leukaemia (AML) whether leukaemic expression of CD33, the target antigen for gemtuzumab ozogamicin (GO), adds prognostic information on GO effectiveness at different d...

    N Khan, R K Hills, P Virgo, S Couzens, N Clark, A Gilkes, P Richardson… in Leukemia (2017)