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Article
Open AccessCorrection: A novel oncogenic BTK isoform is overexpressed in colon cancers and required for RAS-mediated transformation
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Article
Open AccessA novel oncogenic BTK isoform is overexpressed in colon cancers and required for RAS-mediated transformation
Bruton’s tyrosine kinase (BTK) is essential for B-cell proliferation/differentiation and it is generally believed that its expression and function are limited to bone marrow-derived cells. Here, we report the ...
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Article
Fistula in ano: anatomoclinical aspects, surgical therapy and results in 844 patients
Several new therapies, including advancement flaps and fibrin glue, have been proposed for fistula in ano, with conflicting results. Most colorectal surgeons continue to use classic methods, e.g. fistulotomy, ...
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Article
Submucosal reconstructive hemorrhoidectomy (Parks' operation): a 20–year experience
Submucosal reconstructive hemorrhoidectomy has never been a popular operation due to its difficulty and duration, the amount of blood loss, and the risk of incontinence. The main indication for hemorrhoidectom...
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Article
Calibrated lateral internal sphincterotomy for chronic anal fissure
Lateral internal sphincterotomy is an effective procedure for the treatment of anal fissure, but may affected anal continence. We describe a procedure aimed at tailoring the division of the sphincter according...