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Article
Open AccessComparative analysis of mitochondrial genomes of maize CMS-S subtypes provides new insights into male sterility stability
Cytoplasmic male sterility (CMS) is a trait of economic importance in the production of hybrid seeds. In CMS-S maize, exerted anthers appear frequently in florets of field-grown female populations where only c...
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Article
Open AccessTarget-oriented prioritization: targeted selection strategy by integrating organismal and molecular traits through predictive analytics in breeding
Genomic prediction in crop breeding is hindered by modeling on limited phenotypic traits. We propose an integrative multi-trait breeding strategy via machine learning algorithm, target-oriented prioritization ...
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Article
Open AccessA two-phase comprehensive NSCLC prognostic study identifies lncRNAs with significant main effect and interaction
Long noncoding RNA (lncRNA) are involved in regulating physiological behaviors for various malignant tumors, including non-small-cell lung cancer (NSCLC). However, few studies comprehensively evaluated both ln...
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Article
Open AccessThe genetic mechanism of heterosis utilization in maize improvement
In maize hybrid breeding, complementary pools of parental lines with reshuffled genetic variants are established for superior hybrid performance. To comprehensively decipher the genetics of heterosis, we prese...
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Article
Open AccessStalk architecture, cell wall composition, and QTL underlying high stalk flexibility for improved lodging resistance in maize
Stalk fracture caused by strong wind can severely reduce yields in maize. Stalks with higher stiffness and flexibility will exhibit stronger lodging resistance. However, stalk flexibility is rarely studied in ...
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Article
Open AccessCUBIC: an atlas of genetic architecture promises directed maize improvement
Identifying genotype-phenotype links and causative genes from quantitative trait loci (QTL) is challenging for complex agronomically important traits. To accelerate maize gene discovery and breeding, we presen...
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Article
Open AccessshinyBN: an online application for interactive Bayesian network inference and visualization
High-throughput technologies have brought tremendous changes to biological domains, and the resulting high-dimensional data has also posed enormous challenges to computational science. A Bayesian network is a ...
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Article
Open AccessMap** of a major QTL for salt tolerance of mature field-grown maize plants based on SNP markers
Salt stress significantly restricts plant growth and production. Maize is an important food and economic crop but is also a salt sensitive crop. Identification of the genetic architecture controlling salt tole...
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Article
Open AccessStability SCAD: a powerful approach to detect interactions in large-scale genomic study
Evidence suggests that common complex diseases may be partially due to SNP-SNP interactions, but such detection is yet to be fully established in a high-dimensional small-sample (small-n-large-p) study. A numb...