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On-demand drug quantification: an increasing need in pediatric patients

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  1. Article

    Down Syndrome B-Lymphocyte Subpopulations, Intrinsic Defect or Decreased T-Lymphocyte Help

    Down syndrome (DS) is known for increased incidence of respiratory infections and autoimmune diseases, indicating impaired immunity. Until now, attention has been mainly focused on T lymphocytes. Therefore, we...

    Ruud H J Verstegen, Maaike A A Kusters, Eugenie F A Gemen… in Pediatric Research (2010)

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  2. Article

    Both Normal Memory Counts and Decreased Naive Cells Favor Intrinsic Defect Over Early Senescence of Down Syndrome T Lymphocytes

    Because of their increased malignancies, autoimmune diseases, and infections, patients with Down syndrome (DS) show features of immunodeficiency. The DS thymus and T lymphocyte subsets have indeed proven to be...

    Maaike A A Kusters, Eugenie F A Gemen, Ruud H J Verstegen… in Pediatric Research (2010)

    Download PDF (245 KB) View Article