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within Rui Kuang Remove this filter Science, Humanities and Social Sciences, multidisciplinary Remove this filter

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  1. Article

    Open Access

    GNTD: reconstructing spatial transcriptomes with graph-guided neural tensor decomposition informed by spatial and functional relations

    Spatially-resolved RNA profiling has now been widely used to understand cells’ structural organizations and functional roles in tissues, yet it is challenging to reconstruct the whole spatial transcriptomes du...

    Tianci Song, Charles Broadbent, Rui Kuang in Nature Communications (2023)

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  2. No Access

    Article

    mRNA 3′-UTR shortening is a molecular signature of mTORC1 activation

    Mammalian target of rapamycin (mTOR) enhances translation from a subset of messenger RNAs containing distinct 5′-untranslated region (UTR) sequence features. Here we identify 3′-UTR shortening of mRNAs as an a...

    Jae-Woong Chang, Wei Zhang, Hsin-Sung Yeh, Ebbing P. de Jong… in Nature Communications (2015)