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Astragalus polysaccharide alleviates polycystic ovary syndrome by reducing insulin resistance and oxidative stress and increasing the diversity of gut microbiota

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  1. Article

    Open Access

    Letter to the Editor Regarding: Spesolimab Efficacy and Safety in Patients with Moderate-to-Severe Palmoplantar Pustulosis: A Multicentre, Double-Blind, Randomised, Placebo-Controlled, Phase IIb, Dose-Finding Study

    Ruiyao Hu, Yue Wang, Fanzhang Meng, Zhimin Lin, Naigang Chen in Dermatology and Therapy (2024)

  2. Article

    Open Access

    Factors associated with damages and repair costs of reusable flexible bronchoscopes in pediatrics in China

    Frequent repairs of pediatric flexible bronchoscopes can lead to a huge financial burden for the hospital. This study aimed to investigate the common causes of the failures in pediatric flexible bronchoscopes ...

    Ruixue Hu, Yanhua Chen, Sixin Jiang, Ting Hu, Juanli Huang, Lu Zhang in BMC Pediatrics (2024)

  3. Article

    Open Access

    Predictive value of estimated plasma volume for postoperative hypotension in percutaneous intramyocardial septal radiofrequency ablation treating for hypertrophic obstructive cardiomyopathy

    Estimated plasma volume status (ePVS) estimated by the Duarte formula is associated with clinical outcomes in patients with heart failure. It remains unclear the predictive value of the ePVS to the postoperati...

    Bo Shan, **g Li, Zhangwei Shi, Chao Han, Juan Zhang in BMC Cardiovascular Disorders (2024)

  4. Article

    Lipotoxicity-polarised macrophage-derived exosomes regulate mitochondrial fitness through Miro1-mediated mitophagy inhibition and contribute to type 2 diabetes development in mice

    Insulin resistance is a major pathophysiological defect in type 2 diabetes and obesity. Numerous experimental and clinical studies have provided evidence that sustained lipotoxicity-induced mitophagy deficienc...

    Jian-Ming Li, **anyu Li, Lawrence W. C. Chan, Ruinian Hu, Tian Zheng in Diabetologia (2023)

  5. Article

    Open Access

    Novel diagnostic biomarkers of oxidative stress, immune- infiltration characteristics and experimental validation of SERPINE1 in colon cancer

    Colon cancer (CC) is a prevalent malignant tumor that affects the colon in the gastrointestinal tract. Its aggressive nature, strong invasiveness, and rapid progression make it a significant health concern. In...

    Kaisheng Yuan, Di Hu, **aocong Mo, Ruiqi Zeng, Bing Wu, Zunhao Zhang in Discover Oncology (2023)

  6. Article

    Open Access

    Retraction Note: The LMCD1-AS1/miR-526b-3p/OSBPL5 axis promotes cell proliferation, migration and invasion in non-small cell lung cancer

    Rui Hu, Yankai Yu, Haining Wang in BMC Pulmonary Medicine (2023)

  7. Article

    Open Access

    Identification of immune-related target and prognostic biomarkers in PBMC of hepatocellular carcinoma

     Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related deaths worldwide, and is characterized by insidious onset, rapid progression, and poor prognosis. Immunotherapy is a first-line trea...

    Rui Hu, Wei Zhang, Zhiyi Han, Mengqing Ma, Qi Huang, Minling Lv in BMC Gastroenterology (2023)

  8. Article

    Open Access

    Precise diagnosis and ty** of early-stage renal immunoglobulin-derived amyloidosis by label-free quantification of parallel reaction monitoring-based targeted proteomics

    Early diagnosis and ty** are crucial for improving the prognosis of patients with renal amyloidosis. Currently, Untargeted proteomics based precise diagnosis and ty** of amyloid deposits are crucial for gu...

    Yuan Li, Ying Zhang, **n** Zhou, **nli Xue, Muxi Wang, Dedong Kang in BMC Nephrology (2023)

  9. Article

    Open Access

    Sensation of pleasant touch: from molecules to circuits and behaviours

    Ruining Hu, Rongfeng K. Hu in Signal Transduction and Targeted Therapy (2022)

  10. Article

    Open Access

    Effect of intratracheal dexmedetomidine combined with ropivacaine on postoperative sore throat: a prospective randomised double-blinded controlled trial

    The present study aimed to investigate whether intratracheal dexmedetomidine combined with ropivacaine reduces the severity and incidence of postoperative sore throat after tracheal intubation under general an...

    **gyi Niu, Rui Hu, Na Yang, Yan He, Hao Sun, Rende Ning, Junma Yu in BMC Anesthesiology (2022)

  11. Article

    Research progress in laboratory detection of SARS-CoV-2

    Nucleic acid testing is a reliable method for diagnosing viral infection in clinical samples. However, when the number of cases is huge and there are individual differences in the virus itself, the probability...

    Hao-jia Wang, Yang-hui **ang, Rui Hu, Rui Ji in Irish Journal of Medical Science (1971 -) (2022)

  12. Article

    Open Access

    RETRACTED ARTICLE: The LMCD1-AS1/miR-526b-3p/OSBPL5 axis promotes cell proliferation, migration and invasion in non-small cell lung cancer

    To explore the specific role and regulatory mechanism of oxysterol binding protein like 5 (OSBPL5) in non-small cell lung cancer (NSCLC).

    Rui Hu, Yankai Yu, Haining Wang in BMC Pulmonary Medicine (2022)

  13. Article

    Open Access

    A ten-genes-based diagnostic signature for atherosclerosis

    Atherosclerosis is the leading cause of cardiovascular disease with a high mortality worldwide. Understanding the atherosclerosis pathogenesis and identification of efficient diagnostic signatures remain major...

    Feng Zhu, Lili Zuo, Rui Hu, ** Wang, Zhihua Yang, **n Qi in BMC Cardiovascular Disorders (2021)

  14. Article

    Antihypertensive treatment with ACEI/ARB of patients with COVID-19 complicated by hypertension

    Gang Li, Rui Hu, Xuejiao Zhang in Hypertension Research (2020)

  15. Article

    Open Access

    Acupuncture techniques for COPD: a systematic review

    This is the second part of a large spectrum systematic review which aims to identify and assess the evidence for the efficacy of non-pharmacological acupuncture techniques in the treatment of chronic obstructi...

    Carles Fernández-Jané, Jordi Vilaró, Yutong Fei in BMC Complementary Medicine and Therapies (2020)

  16. Article

    Open Access

    A comparison between the Disposcope endoscope and fibreoptic bronchoscope for nasotracheal intubation: a randomized controlled trial

    Nasotracheal intubation (NTI) is frequently performed for oral and maxillofacial surgeries. This study evaluated whether NTI is easier when guided by Disposcope endoscopy or fibreoptic bronchoscopy.

    Junma Yu, Rui Hu, Lining Wu, Peng Sun, Zhi Zhang in BMC Anesthesiology (2019)

  17. Article

    Open Access

    Autonomic remodeling may be responsible for decreased incidence of aortic dissection in STZ-induced diabetic rats via down-regulation of matrix metalloprotease 2

    Epidemiological studies reported that diabetic patients had a lower incidence of aortic dissection (AD), but the definite mechanism is unknown. We aim to investigate the possible protective effect of diabetes ...

    Rui Hu, Zhiwei Wang, Zongli Ren, Min Liu in BMC Cardiovascular Disorders (2016)

  18. Article

    Open Access

    Studies on the purification of polypeptide from sika antler plate and activities of antitumor

    We isolated a novel monomeric peptide from antler plate polypeptide (APP) of sika deer and found that it inhibited rat breast cancer cell proliferation and telomerase activity.

    Wei Hu, Lin Qi, Yu H. Tian, Rui Hu, Lei Wu in BMC Complementary and Alternative Medicine (2015)