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Article
Open AccessEpithelial cells derived exosomal miR-203a-3p facilitates stromal inflammation of type IIIA chronic prostatitis/chronic pelvic pain syndrome by targeting DUSP5 and increasing MCP-1 generation
Increased proinflammatory cytokines and infiltration of inflammatory cells in the stroma are important pathological features of type IIIA chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS-A), and the i...
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Article
Open AccessGlucocorticoid nanoformulations relieve chronic pelvic pain syndrome and may alleviate depression in mice
Chronic pelvic pain syndrome (CPPS) is a typical symptom of chronic prostatitis (CP) in males that may cause abnormal urination, sexual dysfunction, or depression and significantly affect the quality of life o...
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Article
Open AccessMultiplexed evaluation of immunity against SARS-CoV-2 variants using surface enhanced fluorescence from a nanostructured plasmonic chip
Generated by the immune system post-infection or through vaccination, the effectiveness of antibodies against emerging SARS-CoV-2 variants is crucial for protecting individuals from the COVID-19 pandemic. Here...
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Article
Telomere G-triplex lights up Thioflavin T for RNA detection: new wine in an old bottle
Few reports are found working on the features and functions of the human telomere G-triplex (ht-G3) though the telomere G-quadruplex has been intensely studied and widely implemented to develop various biosens...
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Article
Open AccessActive-site engineering of ω-transaminase from Ochrobactrum anthropi for preparation of L-2-aminobutyric acid
The unnatural amino acid, L-2-aminobutyric acid (L-ABA) is an essential chiral building block for various pharmaceutical drugs, such as the antiepileptic drug levetiracetam and the antituberculosis drug ethamb...
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Article
Open AccessHighly stable organic photothermal agent based on near-infrared-II fluorophores for tumor treatment
The aim to develop a highly stable near-infrared (NIR) photoinduced tumor therapy agent stems from its considerable potential for biological application. Due to its long wavelength, biological imaging exhibits...
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Article
Open AccessThe Chinese public’s awareness and attitudes toward genetically modified foods with different labeling
This paper analyzes the awareness and attitudes of the Chinese public toward genetically modified (GM) foods with different types of labeling and evaluates the impact of public confidence in the government man...
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Article
Open AccessCardiomyocyte-targeted and 17β-estradiol-loaded acoustic nanoprobes as a theranostic platform for cardiac hypertrophy
Theranostic perfluorocarbon nanoprobes have recently attracted attention due to their fascinating versatility in integrating diagnostics and therapeutics into a single system. Furthermore, although 17β-estradi...
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Article
Open AccessIntegrated analysis of transcriptome and metabolites reveals an essential role of metabolic flux in starch accumulation under nitrogen starvation in duckweed
Duckweed is considered a promising source of energy due to its high starch content and rapid growth rate. Starch accumulation in duckweed involves complex processes that depend on the balanced expression of ge...
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Article
Open AccessUltrasound-mediated synthesis of N,N-bis(phenacyl)aniline under solvent-free conditions
An efficient method for the synthesis of N,N-bis(phenacyl)anilines was developed via smooth condensation of anilines with α-bromoacetophenones in the presence of sodium carbonate as acid acceptor and polyethylene...
