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Article
Open AccessCirculating levels of asprosin in children with obesity: a systematic review and meta-analysis
Prior studies reported that elevated asprosin level was associated with obesity in adults and animal models. However, the relationship between asprosin level and children with obeisty remains controversial. Th...
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Article
Open AccessA newly discovered glycosyltransferase gene UGT88A1 affects growth and polysaccharide synthesis of Grifola frondosa
Grifola frodosa polysaccharides, especially β-D-glucans, possess significant anti-tumor, antioxidant and immunostimulatory activities. However, the synthesis mechanism remains to be elucidated. A newly discovered...
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Article
Open AccessEffect of non-surgical periodontal treatment on cytokines/adipocytokines levels among periodontitis patients with or without obesity: a systematic review and meta-analysis
The objective of this systematic review and meta-analysis was to evaluate the effects of non-surgical periodontal therapy (NSPT) on inflammatory-related cytokines/adipocytokines in periodontitis patients with ...
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Article
Open AccessEfficacy and safety of self-administered acupressure on symptoms, quality of life and nasal mucosal function in patients with perennial allergic rhinitis: study protocol for a randomized controlled exploratory trial
Allergic rhinitis is a global health problem that can potentially be managed through acupressure. Our clinical observations have identified Allergic Rhinitis Acupressure Therapeutic (ARAT) as a novel acupressu...
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Article
Open AccessAssociation between lipid metabolism and periodontitis in obese patients: a cross-sectional study
To investigate the association between clinical periodontal parameters of periodontitis, serum lipid metabolism markers and adipokines’ levels in patients with obesity and periodontitis.
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Article
Open AccessPrevious pulmonary infection impacts thoracoscopic procedure outcomes in patients with congenital lung malformations: a retrospective cohort study
Patients with congenital lung malformations (CLMs) are at high risk for develo** pulmonary infection. Nonetheless, prophylactic surgical excision of asymptomatic CLMs is controversial and often delayed to sy...
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Article
Open AccessCorrection: JMJD2C promotes colorectal cancer metastasis via regulating histone methylation of MALAT1 promoter and enhancing β-catenin signaling pathway
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Article
In situ food-borne pathogen sensors in a nanoconfined space by surface enhanced Raman scattering
The incidence of disease arising from food-borne pathogens is increasing continuously and has become a global public health problem. Rapid and accurate identification of food-borne pathogens is essential for a...
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Article
Open AccessStructural studies of phosphorylation-dependent interactions between the V2R receptor and arrestin-2
Arrestins recognize different receptor phosphorylation patterns and convert this information to selective arrestin functions to expand the functional diversity of the G protein-coupled receptor (GPCR) superfam...
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Article
Open AccessMetapristone (RU486-derivative) inhibits endometrial cancer cell progress through regulating miR-492/Klf5/Nrf1 axis
Endometrial cancer is an invasive gynecological cancer prevalent in the world. The pathogenesis of endometrial cancer is related to multiple levels of regulation, referring to oestrogen, tumor-suppressor gene ...
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Article
Structures of the glucocorticoid-bound adhesion receptor GPR97–Go complex
Adhesion G-protein-coupled receptors (GPCRs) are a major family of GPCRs, but limited knowledge of their ligand regulation or structure is available1–3. Here we report that glucocorticoid stress hormones activate...
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Article
Open AccessPrimary tumors release ITGBL1-rich extracellular vesicles to promote distal metastatic tumor growth through fibroblast-niche formation
Tumor metastasis is a hallmark of cancer. Metastatic cancer cells often reside in distal tissues and organs in their dormant state. Mechanisms underlying the pre-metastatic niche formation are poorly understoo...
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Article
Open AccessAdaptor protein LNK promotes anaplastic thyroid carcinoma cell growth via 14-3-3 ε/γ binding
Rapid progression contributes to treatment failure in anaplastic thyroid carcinoma (ATC) patients. In a preliminary study, we demonstrated that some hematopoietic factors may be involved in the progression of ...
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Article
Open AccessCyclic compression emerged dual effects on the osteogenic and osteoclastic status of LPS-induced inflammatory human periodontal ligament cells according to loading force
Appropriate mechanical stimulation is essential for bone homeostasis in healthy periodontal tissues. While the osteogenesis and osteoclast differentiation of inflammatory periodontal ligament cells under diffe...
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Article
Open AccessJMJD2C promotes colorectal cancer metastasis via regulating histone methylation of MALAT1 promoter and enhancing β-catenin signaling pathway
Our previous work demonstrated that lncRNA-MALAT1 was overexpressed in recurrent colorectal cancer (CRC) and metastatic sites in post-surgical patients. However, the upstream regulatory mechanism of MALAT1 is ...
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Article
Open AccessRev-erbα inhibits proliferation by reducing glycolytic flux and pentose phosphate pathway in human gastric cancer cells
Rev-erbα is a nuclear receptor, which regulates circadian rhythm, inflammatory responses and lipid metabolism. We previously showed Rev-erbα reduction in human gastric cancer, which is associated with TMN stag...
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Article
Open AccessPopulation dynamics and habitat use of the Black-necked Crane (Grus nigricollis) in the Yarlung Tsangpo River basin, Tibet, China
The Black-necked Crane (Grus nigricollis) is an internationally threatened crane living on the plateau, mainly in winter, in the Yarlung Tsangpo River basin in Tibet, western China. In the past five years, some e...
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Article
Retraction Note to: Capture-removal model sampling estimation based on big data
The authors have retracted “Capture-removal model sampling estimation based on big data”, Vol. 20, No. 2, June 2017. Upon re-review of the data, the authors identified an incorrect time setting of the Tian** ...
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Article
Open AccessA region-resolved mucosa proteome of the human stomach
The human gastric mucosa is the most active layer of the stomach wall, involved in food digestion, metabolic processes and gastric carcinogenesis. Anatomically, the human stomach is divided into seven regions,...
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Article
Effect of vibration on seepage feeding during low-pressure casting of ZL205A alloy
Appropriate vibration can promote the feeding capacity of gravity casting, but the effect of vibration on the feeding of low-pressure casting is not clear. The effect of vibration on the seepage feeding of ZL2...
