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  1. Article

    Open Access

    Characterizing criticality of proteins by systems dynamics: Escherichia coli central carbon metabolism as a working example

    Systems biology calls for studying system-level properties of genes and proteins rather than their individual chemical/biological properties, regarding the bio-molecules as system components. By characterizing...

    Ru-Dong Li, Lei Liu in BMC Systems Biology (2012)

  2. Article

    Open Access

    An improved kinetic model for the acetone-butanol-ethanol pathway of Clostridium acetobutylicum and model-based perturbation analysis

    Comprehensive kinetic models of microbial metabolism can enhance the understanding of system dynamics and regulatory mechanisms, which is helpful in optimizing microbial production of industrial chemicals. Clostr...

    Ru-Dong Li, Yuan-Yuan Li, Ling-Yi Lu, Cong Ren, Yi-Xue Li, Lei Liu in BMC Systems Biology (2011)