21 Result(s)
within
Ru-**a Zhao
Life Sciences
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Article
Di- and tri-methylation of histone H3K36 play distinct roles in DNA double-strand break repair
Histone H3 Lys36 (H3K36) methylation and its associated modifiers are crucial for DNA double-strand break (DSB) repair, but the mechanism governing whether and how different H3K36 methylation forms impact repa...
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Article
Longitudinal aortic strain, ventriculo-arterial coupling and fatty acid oxidation: novel insights into human cardiovascular aging
Aging-induced aortic stiffness has been associated with altered fatty acid metabolism. We studied aortic stiffness using cardiac magnetic resonance (CMR)-assessed ventriculo-arterial coupling (VAC) and novel a...
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Article
QTL-seq and transcriptomic integrative analyses reveal two positively regulated genes that control the low-temperature germination ability of MTP–maize introgression lines
Two candidate genes (ZmbZIP113 and ZmTSAH1) controlling low-temperature germination ability were identified by QTL-seq and integrative transcriptomic analyses. The functional verification results showed that t...
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Article
Open AccessGut microbiota differs between two cold-climate lizards distributed in thermally different regions
The metabolic cold-climate adaption hypothesis predicts that animals from cold environments have relatively high metabolic rates compared with their warm-climate counterparts. However, studies testing this hyp...
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Article
Open AccessNovel cleavage sites identified in SARS-CoV-2 spike protein reveal mechanism for cathepsin L-facilitated viral infection and treatment strategies
The spike (S) protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an important target for vaccine and drug development. However, the rapid emergence of variant strains with mutated S pro...
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Article
First report of Capsicum frutescens endornavirus 1 infecting pepper in China
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Article
Open AccessNR4A1 enhances MKP7 expression to diminish JNK activation induced by ROS or ER-stress in pancreatic β cells for surviving
Under adverse conditions, such as sustained or chronic hyperglycemia or hyperlipidemia, ROS (reactive oxygen species) or/and ER-stress (endoplasmic reticulum stress) will be induced in pancreatic β cells. ROS ...
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Article
Population structure and selection pressure analysis among Sugarcane yellow leaf virus isolates based on P0 and P1 sequences
Yellow leaf of sugarcane is caused by Sugarcane yellow leaf virus (SCYLV) and has been a threat to global sugar industry. Understanding the diversity and genetic structure of plant virus populations may help to d...
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Article
Identification of a new maize inflorescence meristem mutant and association analysis using SLAF-seq method
Maize inflorescence provides a useful model to study the genetic and molecular control of meristems. Many classical maize mutants were described last century, providing important insights into the mechanism of...
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Article
Cloning and characterisation of a pepper aquaporin, CaAQP, which reduces chilling stress in transgenic tobacco plants
Ubiquitous cell membrane proteins called aquaporins are members of major intrinsic proteins (MIPs), which control the specific transport of water molecules across cell membranes. A pepper aquaporin gene (CaAQP), ...
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Article
Open AccessMolecular footprints of domestication and improvement in soybean revealed by whole genome re-sequencing
Artificial selection played an important role in the origin of modern Glycine max cultivars from the wild soybean Glycine soja. To elucidate the consequences of artificial selection accompanying the domestication...
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Article
Effects of recombinant hIL-2-Luffin P1 immunotoxin combining with arotinoid ethylester on the proliferation and apoptosis of Hut-78 cells
Prokaryotic expression vectors pET32a (+)-hIL-2-Luffin P1 and pET32a(+)-Luffin P1 were constructed by gene engineering, followed by induced expression, purification and identification of hIL-2-Luffin P1 and Lu...
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Article
Open AccessAdenylate kinase 2 (AK2) promotes cell proliferation in insect development
Adenylate kinase 2 (AK2) is a phosphotransferase that catalyzes the reversible reaction 2ADP(GDP) ↔ ATP(GTP) + AMP and influences cellular energy homeostasis. However, the role of AK2 in regulating cell prolif...
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Article
Downstream processing of biotechnological produced succinic acid
Succinic acid is a promising chemical which has a wide range of applications and can be biologically produced. The separation of succinic acid from fermentation broth makes more than 50 % of the total costs in...
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Article
Antioxidant effect of a phytoestrogen equol on cultured muscle cells of embryonic broilers
Previous studies have shown that the in ovo injection of equol can markedly improve the water-holding capacity of muscles of broilers chickens at 7 wk of age through promotion of the antioxidant status. We aim...
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Article
Effect of glucocorticoids pretreatment on steroidogenic capacity of adrenocortical cells isolated from Meishan piglets
The present in vitro experiment was designed to test whether 48 h of pretreatment with glucocorticoids, cortisol, or dexamethasone (DEX), would affect basal and corticotrophin (ACTH) stimulated (24 h) cortisol...
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Article
A Series of Novel Rare Earth Molybdotungstosilicate Heteropolyoxometalates Binding to Bovine Serum Albumin: Spectroscopic Approach
Heteropolyoxometalate complexes have been widely applied in many fields. In this paper, the interaction between a series of novel rare earth molybdotungstosilicate heteropolyoxometalates, K10H3[Ln(SiMo6W5O39)2]·x...
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Article
Biological Activation of Heteropoly Complex of Molybdotungstosilicate Containing Lanthanum K10H3La(SiMo6W5O39)2⋅26H2O: Spectroscopic Approach and Microcalorimetry
In this paper, the biological activation of heteropoly complex of molybdotungstosilicate containing lanthanum K10H3La(SiMo6W5O39)2⋅26H2O (LaW5) was investigated by spectroscopic approach and microcalorimetry unde...
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Chapter and Conference Paper
Poster Summaries
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Article
Habitat Degradation of Rhinopithecus bieti in Yunnan, China
Black-and-white snub-nosed monkeys (Rhinopithecus bieti) are endemic to the Trans-Himalayas in Northwest Yunnan and Southeast Tibet between the upper Yangtze and Mekong Rivers. Based on field surveys and previous...
