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Article
Open AccessLigand-induced nuclear translocation of S1P1 receptors mediates Cyr61 and CTGF transcription in endothelial cells
Sphingosine-1-phosphate (S1P) receptor subtype 1 (S1P1), a G-protein coupled receptor (GPCR), regulates many biological activities of endothelial cells (ECs). In this report, we show that S1P1 receptors are prese...
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Article
Mechanisms of Periodic Acceleration Induced Endothelial Nitric Oxide Synthase (eNOS) Expression and Upregulation Using an In Vitro Human Aortic Endothelial Cell Model
Following severe injury in cases like ischemia reperfusion, recovery and tissue repair are compromised due to microvascular failure. Nitric oxide (NO) has been shown to have both vasodilatory and anti-inflamma...