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    Exploring the binding pocket for pyridopyrimidine ligands at the CCK1 receptor by molecular docking

    Pyridopyrimidine-based analogues are among the most highly potent and selective antagonists of cholecystokinin receptor subtype-1 (CCK1R) described to date. To better understand the structural and chemical fea...

    Amel Toumi-Maouche, Boubekeur Maouche, Safia Taïri-Kellou in Journal of Molecular Modeling (2008)

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    Studies on the synthesis of β-keto esters derived from dipeptides: search for a low-epimerizing method

    β-Keto esters derived from dipeptides areprepared by application of common methodologiesemployed for the synthesis of amino acid-derivedβ-keto esters; however, epimerization of theC-terminal residue occurred t...

    Rosario Patiño-Molina, Mercedes Martín-Martínez in Letters in Peptide Science (2000)

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    Similarity Study on Peptide γ-turn Conformation Mimetics

    The ability of a series of structures to mimic the geometric and electronic properties of an ideal γ–turn has been studied. Initially, an exhaustive conformational analysis was carried out using the molecular ...

    Ibon Alkorta, Maria Luisa Suarez, Rosario Herranz in Molecular modeling annual (1996)

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    Constrained C-terminal hexapeptide neurotensin analogues containing a 3-oxoindolizidine skeleton

    In order to enforce different spatial orientations in the C-terminal hexapeptide of neurotensin (NT8−13) and to gain information about the importance of the 10–11 peptide bond for binding to NT receptors, the Pro

    M. Teresa García-López, Ibon Alkorta, M. José Domínguez in Letters in Peptide Science (1995)