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Chapter
PACAP27 Analogues Incorporating Type II/II’ β-Turn Mimetics
Pituitary adenyl cyclase-activating peptide (PACAP) is a member of the superfamily of regulatory peptides including secretin, glucagon, VIP and GRF [1]. It exists in two bioactive forms, PACAP38 and its shorte...
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Article
Studies on the synthesis of β-keto esters derived from dipeptides: search for a low-epimerizing method
β-Keto esters derived from dipeptides areprepared by application of common methodologiesemployed for the synthesis of amino acid-derivedβ-keto esters; however, epimerization of theC-terminal residue occurred t...
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Article
Constrained C-terminal hexapeptide neurotensin analogues containing a 3-oxoindolizidine skeleton
In order to enforce different spatial orientations in the C-terminal hexapeptide of neurotensin (NT8−13) and to gain information about the importance of the 10–11 peptide bond for binding to NT receptors, the Pro