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Chapter
β-Lactams Through Single Bond Ring Closing: Methods, Transformations and Bioactivity
Because the renewed interest of β–lactams in organic and medicinal chemistry, research in this field continues producing new appealing progresses. This chapter will cover significant success in the synthesis o...
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Article
Exploring the binding pocket for pyridopyrimidine ligands at the CCK1 receptor by molecular docking
Pyridopyrimidine-based analogues are among the most highly potent and selective antagonists of cholecystokinin receptor subtype-1 (CCK1R) described to date. To better understand the structural and chemical fea...
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Article
Similarity Study on Peptide γ-turn Conformation Mimetics
The ability of a series of structures to mimic the geometric and electronic properties of an ideal γ–turn has been studied. Initially, an exhaustive conformational analysis was carried out using the molecular ...