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Single-cell transcriptome profiling reveals neutrophil heterogeneity in homeostasis and infection

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    Open Access

    Inflammasome-mediated GSDMD activation facilitates escape of Candida albicans from macrophages

    Candida albicans is the most common cause of fungal sepsis. Inhibition of inflammasome activity confers resistance to polymicrobial and LPS-induced sepsis; however, inflammasome signaling appears to protect again...

    **onghui Ding, Hiroto Kambara, Rongxia Guo, Apurva Kanneganti in Nature Communications (2021)