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  1. Article

    Open Access

    Inflammasome-mediated GSDMD activation facilitates escape of Candida albicans from macrophages

    Candida albicans is the most common cause of fungal sepsis. Inhibition of inflammasome activity confers resistance to polymicrobial and LPS-induced sepsis; however, inflammasome signaling appears to protect again...

    **onghui Ding, Hiroto Kambara, Rongxia Guo, Apurva Kanneganti… in Nature Communications (2021)

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  2. No Access

    Article

    Single-cell transcriptome profiling reveals neutrophil heterogeneity in homeostasis and infection

    The full neutrophil heterogeneity and differentiation landscape remains incompletely characterized. Here, we profiled >25,000 differentiating and mature mouse neutrophils using single-cell RNA sequencing to pr...

    Xuemei **e, Qiang Shi, Peng Wu, **aoyu Zhang, Hiroto Kambara, Jiayu Su… in Nature Immunology (2020)