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Article
Open AccessNano friction behaviour between magnetic materials and copper considering the inter-diffusion effect
Copper, permalloy, cobalt, and silicon are the materials that have been widely utilised in magnetic devices. When the size of interest is down to the nanoscale, the inter-diffusion between certain materials be...
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Article
Open AccessZero-shot learning enables instant denoising and super-resolution in optical fluorescence microscopy
Computational super-resolution methods, including conventional analytical algorithms and deep learning models, have substantially improved optical microscopy. Among them, supervised deep neural networks have d...
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Article
Open Access“The Sum Is Greater Than the Parts?”—The Role of Student Covitality in Flourishing
Existing studies have revealed associations of positive psychological traits with human thriving and flourishing. However, how these traits co-occur—known as covitality—and how it relates to flourishing remain...
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Article
Open AccessThe emerging roles of miRNA-mediated autophagy in ovarian cancer
Ovarian cancer is one of the common tumors of the female reproductive organs. It has a high mortality rate, is highly heterogeneous, and early detection and primary prevention are very complex. Autophagy is a ...
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Article
Open AccessEvaluation of disease severity and prediction of severe cases in children hospitalized with influenza A (H1N1) infection during the post-COVID-19 era: a multicenter retrospective study
The rebound of influenza A (H1N1) infection in post-COVID-19 era recently attracted enormous attention due the rapidly increased number of pediatric hospitalizations and the changed characteristics compared to...
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Article
Open AccessHow does the SARS-CoV-2 reinfection rate change over time? The global evidence from systematic review and meta-analysis
There is a significant increase in the number of SARS-CoV-2 reinfection reports in various countries. However, the trend of reinfection rate over time is not clear.
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Article
Open AccessOutcome of chairside CAD/CAM ceramic restorations on endodontically treated posterior teeth: a prospective study
The aim of this study was to evaluate the outcome and risk factors for chairside CAD/CAM full cusp coverage restorations on endodontically treated posterior teeth after 3 years of follow-up.
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Article
Open AccessUmbrella strategy with systemic and intraperitoneal chemotherapy versus systemic chemotherapy in patients with advanced gastric cancer: a multicenter, randomized Phase III clinical trial
We have developed a tridirectional regimen combining intraperitoneal, intravenous, and oral chemotherapy as a treatment for patients with advanced gastric cancer and individualized these chemotherapeutics acco...
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Open AccessSingle-nucleus transcriptome inventory of giant panda reveals cellular basis for fitness optimization under low metabolism
Energy homeostasis is essential for the adaptation of animals to their environment and some wild animals keep low metabolism adaptive to their low-nutrient dietary supply. Giant panda is such a typical low-met...
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Article
Open AccessApplication of non-invasive prenatal testing to 91,280 spontaneous pregnancies and 3477 pregnancies conceived by in vitro fertilization
Many clinical studies based on spontaneous pregnancies (SPs) have demonstrated the superiority of non-invasive prenatal testing (NIPT), and the question of whether this technology is suitable for offspring con...
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Article
Open AccessUltrasound-guided scalp nerve block in anesthesia of children receiving cranial suture reconstruction
Analgesia is very important for children with craniosynostosis who are undergoing cranial suture reconstruction. This study investigated the effectiveness and safety of an analgesic technique based on scalp ne...
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Article
Open AccessImmune regulation and prognosis indicating ability of a newly constructed multi-genes containing signature in clear cell renal cell carcinoma
Clear cell renal cell carcinoma (ccRCC) is the most common renal malignancy, although newly develo** targeted therapy and immunotherapy have been showing promising effects in clinical treatment, the effectiv...
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Article
Open AccessA live-cell image-based machine learning strategy for reducing variability in PSC differentiation systems
The differentiation of pluripotent stem cells (PSCs) into diverse functional cell types provides a promising solution to support drug discovery, disease modeling, and regenerative medicine. However, functional...
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Article
Open AccessCorrection: AHSA1 is a promising therapeutic target for cellular proliferation and proteasome inhibitor resistance in multiple myeloma
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Article
Open AccessFactors influencing bamboo intake of captive giant pandas (Ailuropoda melanoleuca)
Bamboo is the main food source of the giant panda. To increase bamboo intake in captive giant pandas, we studied factors affecting the bamboo intake. Fourteen healthy captive giant pandas in Dujiangyan Base of...
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Article
Open AccessOsteosarcoma transcriptome data exploration reveals STC2 as a novel risk indicator in disease progression
Osteosarcoma has been the most common primary bone malignant tumor in children and adolescents. Despite the considerable improvement in the understanding of genetic events attributing to the rapid development ...
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Article
Open AccessThromboembolism after treatment with 4-factor prothrombin complex concentrate or plasma for warfarin-related bleeding
Limited data exist in large, representative populations about whether the risk of thromboembolic events varies after receiving four-factor human prothrombin complex concentrate (4F-PCC) versus treatment with h...
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Article
Open AccessMycobacterium tuberculosis/Mycobacterium bovis triggered different variations in lipid composition of Bovine Alveolar Macrophages
The lipid composition performs important functions in interaction between macropha-ge and Mycobacterium tuberculosis (MTB)/Mycobacterium bovis (MB). Current understanding regarding the lipid responses of bovine a...
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Article
Open AccessProfiling Fusobacterium infection at high taxonomic resolution reveals lineage-specific correlations in colorectal cancer
The bacterial genus Fusobacterium promotes colorectal cancer (CRC) development, but an understanding of its precise composition at the species level in the human gut and the relevant association with CRC is lacki...
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Article
Open AccessPan-cancer analysis reveals RIPK2 predicts prognosis and promotes immune therapy resistance via triggering cytotoxic T lymphocytes dysfunction
Receptor-interacting protein kinase 2 (RIPK2, also known as RIP2) was reported to be associated with bacterial infections as well as inflammatory responses. However, the role of RIPK2 in prognosis and immunoth...
