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Using Chou’s pseudo amino acid composition based on approximate entropy and an ensemble of AdaBoost classifiers to predict protein subnuclear location

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  1. Article

    Open Access

    The emerging roles of miRNA-mediated autophagy in ovarian cancer

    Ovarian cancer is one of the common tumors of the female reproductive organs. It has a high mortality rate, is highly heterogeneous, and early detection and primary prevention are very complex. Autophagy is a ...

    Yamin Ding, Xuan Huang, Tuo Ji, Cong Qi, Xuzhu Gao, Rongbin Wei in Cell Death & Disease (2024)

  2. Article

    Open Access

    The metabolic flexibility of quiescent CSC: implications for chemotherapy resistance

    Quiescence has been observed in stem cells (SCs), including adult SCs and cancer SCs (CSCs). Conventional chemotherapies mostly target proliferating cancer cells, while the quiescent state favors CSCs escape t...

    Kangchen Chen, Chenzhi Zhang, Sunbin Ling, Rongli Wei, Jianguo Wang in Cell Death & Disease (2021)

  3. Article

    Open Access

    Suppression of steroid 5α-reductase type I promotes cellular apoptosis and autophagy via PI3K/Akt/mTOR pathway in multiple myeloma

    Steroid 5α-reductase type I (SRD5A1) is a validated oncogene in many sex hormone-related cancers, but its role in multiple myeloma (MM) remains unknown. Based on gene expression profiling (GEP) of sequential M...

    Renjie Dou, **jun Qian, Wei Wu, Yanxin Zhang, Yuxia Yuan in Cell Death & Disease (2021)

  4. Article

    Open Access

    MicroRNA-214 promotes hepatic stellate cell activation and liver fibrosis by suppressing Sufu expression

    MicroRNAs (miRNAs) have been demonstrated to modulate cellular processes in the liver. However, the role of miRNAs in liver fibrosis is poorly understood. Because the activation of hepatic stellate cells (HSCs...

    Li** Ma, **aoxue Yang, Rong Wei, Tinghong Ye, Jian-Kang Zhou in Cell Death & Disease (2018)