35 Result(s)
within
Rong** Wei
Life Sciences
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Article
Open AccessThe emerging roles of miRNA-mediated autophagy in ovarian cancer
Ovarian cancer is one of the common tumors of the female reproductive organs. It has a high mortality rate, is highly heterogeneous, and early detection and primary prevention are very complex. Autophagy is a ...
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Open AccessSingle-nucleus transcriptome inventory of giant panda reveals cellular basis for fitness optimization under low metabolism
Energy homeostasis is essential for the adaptation of animals to their environment and some wild animals keep low metabolism adaptive to their low-nutrient dietary supply. Giant panda is such a typical low-met...
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Explore the nucleolus: unveiling the hidden layer with super-resolution microscopy
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Open AccessA live-cell image-based machine learning strategy for reducing variability in PSC differentiation systems
The differentiation of pluripotent stem cells (PSCs) into diverse functional cell types provides a promising solution to support drug discovery, disease modeling, and regenerative medicine. However, functional...
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Establishment of Agrobacterium-mediated transformation system to Juglans sigillata Dode ‘Qianhe-7’
An efficient genetic transformation system is of great significance for verifying gene function and improving plant breeding efficiency by gene engineering. In this study, a stable Agrobacterium mediated genetic ...
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Open AccessGenome-scale transcriptomic insights into the gene co-expression network of seed abortion in triploid Siraitia grosvenorii
Siraitia grosvenorii (Swingle) C. Jeffrey, also known as Luohanguo or monk fruit, is a famous traditional Chinese medicine ingredient with important medicinal value and broad development prospects. Diploid S. gro...
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Open AccessThe metabolic flexibility of quiescent CSC: implications for chemotherapy resistance
Quiescence has been observed in stem cells (SCs), including adult SCs and cancer SCs (CSCs). Conventional chemotherapies mostly target proliferating cancer cells, while the quiescent state favors CSCs escape t...
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Open AccessSuppression of steroid 5α-reductase type I promotes cellular apoptosis and autophagy via PI3K/Akt/mTOR pathway in multiple myeloma
Steroid 5α-reductase type I (SRD5A1) is a validated oncogene in many sex hormone-related cancers, but its role in multiple myeloma (MM) remains unknown. Based on gene expression profiling (GEP) of sequential M...
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Bamboo nutrients and microbiome affect gut microbiome of giant panda
To investigate the relationship between the bamboo including its nutrients and microbiome, and gut microbiome of giant panda, different bamboo species were provided for feeding the giant pandas. Nutrients of b...
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Molecular cloning and functional characterization of a seed-specific VvβVPE gene promoter from Vitis vinifera
The grapevine VvβVPE promoter is specifically expressed in the seed. The − 1306~− 1045 bp core region restricts expression in other tissues and organs.
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Article
HL2 on chromosome 7D of wheat (Triticum aestivum L.) regulates both head length and spikelet number
A major QTL QSpl.nau-7D, named HL2, was validated for its effects on head length and kernel number per spike using NIL, and mapped to a 0.2 cM interval using recombinants.
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Article
Cyathane diterpenoids and drimane sesquiterpenoids with neurotrophic activity from cultures of the fungus Cyathus africanus
Five terpenoids, including two new cyathane diterpenoids neocyathin S (1) and neocyathin T (2), together with three drimane sesquiterpenoids, one known 3β,6β-dihydroxycinnamolide (3), two new ones 3β,6α-dihydroxy...
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Open AccessMicroRNA-214 promotes hepatic stellate cell activation and liver fibrosis by suppressing Sufu expression
MicroRNAs (miRNAs) have been demonstrated to modulate cellular processes in the liver. However, the role of miRNAs in liver fibrosis is poorly understood. Because the activation of hepatic stellate cells (HSCs...
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Article
Pleiotropic effects of the wheat domestication gene Q on yield and grain morphology
Transformation from q to Q during wheat domestication functioned outside the boundary of threshability to increase yield, grains m−2, grain weight and roundness, but to reduce grains per spike/spikelet.
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Open AccessGiant panda reintroduction: factors affecting public support
Reintroducing captive-born individuals of some extirpated flagship animal species is a helpful and remedy measure for promoting biodiversity conservation, and a successful reintroduction relies heavily on publ...
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Open AccessThe 2nd International Conference on Agricultural and Biological Sciences (ABS 2016)
01 The influence of soil salt content on the photosynthetic characteristics of spring wheat with trickle irrigation
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Molecular characterization of melanin-concentrating hormone (MCH) in Schizothorax prenanti: cloning, tissue distribution and role in food intake regulation
Melanin-concentrating hormone (MCH) is a crucial neuropeptide involved in various biological functions in both mammals and fish. In this study, the full-length MCH cDNA was obtained from Schizothorax prenanti by ...
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Positive selection rather than relaxation of functional constraint drives the evolution of vision during chicken domestication
As noted by Darwin, chickens have the greatest phenotypic diversity of all birds, but an interesting evolutionary difference between domestic chickens and their wild ancestor, the Red Junglefowl, is their comp...
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In Vivo Whole-Cell Patch-Clamp Recording in the Zebrafish Brain
Zebrafish (Danio rerio) is a newly emerged vertebrate animal model with a conserved gross architecture of the brain and a rich repertoire of behaviors. Due to the optical transparency and structural simplicity of...
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Article
Open AccessIdentification of novel and conserved microRNAs in Panax notoginseng roots by high-throughput sequencing
MicroRNAs (miRNAs) are small, non-coding RNAs that are important regulators of gene expression, and play major roles in plant development and their response to the environment. Root extracts from Panax notoginsen...
