5 Result(s)

Article

Copy number variations in the genome of the Qatari population

The populations of the Arabian Peninsula remain the least represented in public genetic databases, both in terms of single nucleotide variants and of larger genomic mutations. We present the first high-resolut...

Khalid A. Fakhro, Noha A. Yousri, Juan L. Rodriguez-Flores, Amal Robay… in BMC Genomics (2015)

Article

Cigarette smoking induces small airway epithelial epigenetic changes with corresponding modulation of gene expression

Lauren J Buro-Auriemma, Neil R Hackett, Jacqueline Salit… in Epigenetics & Chromatin (2013)

Article

Inferring genome-wide patterns of admixture in Qataris using fifty-five ancestral populations

Populations of the Arabian Peninsula have a complex genetic structure that reflects waves of migrations including the earliest human migrations from Africa and eastern Asia, migrations along ancient civilizati...

Larsson Omberg, Jacqueline Salit, Neil Hackett, Jennifer Fuller… in BMC Genetics (2012)

Article

RNA-Seq quantification of the human small airway epithelium transcriptome

The small airway epithelium (SAE), the cell population that covers the human airway surface from the 6^th generation of airway branching to the alveoli, is the major site of lung disease caused by smoking. The foc...

Neil R Hackett, Marcus W Butler, Renat Shaykhiev, Jacqueline Salit… in BMC Genomics (2012)

Article

Quality control in microarray assessment of gene expression in human airway epithelium

Microarray technology provides a powerful tool for defining gene expression profiles of airway epithelium that lend insight into the pathogenesis of human airway disorders. The focus of this study was to estab...

Tina Raman, Timothy P O'Connor, Neil R Hackett, Wei Wang, Ben-Gary Harvey… in BMC Genomics (2009)