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  1. Article

    Open Access

    Sustained Remission and Outcomes with Abatacept plus Methotrexate Following Stepwise Dose De-escalation in Patients with Early Rheumatoid Arthritis

    One target of rheumatoid arthritis (RA) treatment is to achieve early sustained remission; over the long term, patients in sustained remission have less structural joint damage and physical disability. We eval...

    Paul Emery, Yoshiya Tanaka, Vivian P. Bykerk in Rheumatology and Therapy (2023)

  2. Article

    Open Access

    The trajectory of clinical responses in patients with early rheumatoid arthritis who achieve sustained remission in response to abatacept: subanalysis of AVERT-2, a randomized phase IIIb study

    AVERT-2 (a phase IIIb, two-stage study) evaluated abatacept + methotrexate versus methotrexate alone, in methotrexate-naive, anti-citrullinated protein antibody-positive patients with early (≤ 6 months), activ...

    Paul Emery, Yoshiya Tanaka, Vivian P. Bykerk in Arthritis Research & Therapy (2023)

  3. Article

    Open Access

    Maintenance of antibody response to diphtheria/tetanus vaccine in patients aged 2–5 years with polyarticular-course juvenile idiopathic arthritis receiving subcutaneous abatacept

    Patients with polyarticular-course juvenile idiopathic arthritis (pJIA), receiving disease-modifying anti-rheumatic drugs with immunosuppressive effects, may be at increased risk of vaccine-preventable infecti...

    Hermine I. Brunner, Nikolay Tzaribachev, Gabriel Vega Cornejo in Pediatric Rheumatology (2020)

  4. Article

    Open Access

    Effectiveness of adalimumab in treating patients with ankylosing spondylitis associated with enthesitis and peripheral arthritis

    The purpose of this study was to investigate the effectiveness of adalimumab in enthesitis and peripheral arthritis in patients with ankylosing spondylitis (AS).

    Martin Rudwaleit, Pascal Claudepierre, Martina Kron in Arthritis Research & Therapy (2010)

  5. Article

    Open Access

    Assessment of radiographic progression in the spines of patients with ankylosing spondylitis treated with adalimumab for up to 2 years

    Ankylosing spondylitis (AS) is a chronic rheumatic disease associated with spinal inflammation that subsequently leads to progression of structural damage and loss of function. The fully human anti-tumor necro...

    Désirée van der Heijde, David Salonen, Barbara N Weissman in Arthritis Research & Therapy (2009)