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Article
Treatment of Unresectable Primary and Metastatic Liver Cancer with Yttrium-90 Microspheres (TheraSphere®): Assessment of Hepatic Arterial Embolization
In Canada and Europe, yttrium-90 microspheres (TheraSphere®; MDS Nordion, Ottawa, Canada) are a primary treatment option for primary and secondary hepatic malignancies. We present data from 30 patients with hepat...
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Article
Radioembolization with 90Y Microspheres: Angiographic and Technical Considerations
The anatomy of the mesenteric system and the hepatic arterial bed has been demonstrated to have a high degree of variation. This is important when considering pre-surgical planning, catheterization, and trans-...
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Article
Radiographic Response to Yttrium-90 Radioembolization in Anterior Versus Posterior Liver Segments
The purpose of our study was to determine if preferential radiographic tumor response occurs in tumors located in posterior versus anterior liver segments following radioembolization with yttrium-90 glass micr...
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Article
Internal radioembolization for colorectal carcinoma liver metastases
Colorectal cancer remains a significant cause of morbidity and mortality. Treatment options and therapeutic interventions for patients who have disease progression despite treatment with systemic therapies hav...
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Article
Radiologic findings following Y90 radioembolization for primary liver malignancies
A therapy gaining rapid clinical adoption involves radioembolization with the use of Yttrium-90 (90Y) microspheres. The 20–60 μm-sized microspheres are injected trans-arterially and flow to hepatic tumors give...
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Article
A Simple Fluoroscopic Approach to Percutaneous Transgastric Cystgastrostomy with Internalized Drainage Catheter for Treatment of Pancreatic Pseudocysts: Report of Two Cases
With the emergence of minimally invasive techniques, percutaneous drainage has been applied to the management of symptomatic pancreatic pseudocysts in lieu of conventional surgical or endoscopic therapy. Percu...
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Article
Hepatic Abscess After Yttrium-90 Radioembolization for Islet-Cell Tumor Hepatic Metastasis
Infectious complications after yttrium-90 (y-90) radioembolization of hepatic tumors are rare. Most reports describe hepatic abscesses as complications of other locoregional therapies, such as transcatheter ar...
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Article
How to Interpret Thyroid Biopsy Results: A Three-Year Retrospective Interventional Radiology Experience
Results of thyroid biopsy determine whether thyroid nodule resection is appropriate and the extent of thyroid surgery. At our institution we use 20/22-gauge core biopsy (CBx) in conjunction with fine-needle as...
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Article
Radiologic–Pathologic Correlation of Hepatocellular Carcinoma Treated with Chemoembolization
To correlate posttreatment radiologic and pathologic findings in patients who underwent transarterial chemoembolization before transplantation or resection. Thirty-five patients with postchemoembolization foll...
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Article
Treating and Downstaging Hepatocellular Carcinoma in the Caudate Lobe with Yttrium-90 Radioembolization
This study was designed to determine the technical feasibility, safety, efficacy, and potential to downstage patients to within transplantation criteria when treating patients with hepatocellular carcinoma (HC...
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Reference Work Entry In depth
Embolic Therapies
Primary and secondary liver cancers pose a challenge in terms of treatment options for the following reasons: (1) most patients are unresectable at presentation not only due to tumor stage but also because of ...
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Chapter
Yttrium 90 Microspheres for the Treatment of Hepatocellular Carcinoma
Yttrium-90 microspheres are radioactive particles which are increasingly being employed for treating patients with unresectable hepatocellular carcinoma (HCC). The procedure is called radioembolization. It inv...
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Reference Work Entry In depth
Chemoembolization and Radioembolization in the Treatment of Primary Liver Cancers
The incidence of hepatocellular carcinoma is increasing worldwide. Chemoembolization and radioembolization represent two novel transarterial therapies which are primarily based on a similar basic concept of th...
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Article
Imaging tumor response following liver-directed intra-arterial therapy
Liver-directed intra-arterial therapies are palliative treatment options for patients with unresectable liver cancer; their use has also resulted in patients being downstaged leading to curative resection and ...
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Article
Sustained safety and efficacy of extended-shelf-life 90Y glass microspheres: long-term follow-up in a 134-patient cohort
To validate our initial pilot study and confirm sustained safety and tumor response of extended-shelf-life 90Y glass microspheres. We hypothesized that for the same planned tissue dose, the increase in number of ...
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Article
Twelve-year experience of radioembolization for colorectal hepatic metastases in 214 patients: survival by era and chemotherapy
The aim of this study was to analyze the safety, treatment characteristics and survival outcomes of Yttrium-90 (Y90) radioembolization for unresectable colorectal carcinoma (CRC) liver metastases refractory to...
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Article
Can volumetric ADC measurement help predict response to Y90 radioembolization in HCC?
Aim: To compare changes in RECIST, anatomical volume, mRECIST, and volumetric diffusion-weighted Imaging parameters (3D apparent diffusion coefficient (ADC) measurements), with pathologic...
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Article
Gastric injury from 90Y to left hepatic lobe tumors adjacent to the stomach: fact or fiction?
Radioembolization with 90Y microspheres is a locoregional radiation therapy for unresectable hepatic neoplasm. Non-target delivery of 90Y microspheres resulting in gastrointestinal (GI) symptoms is a recognized c...
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Chapter
Locoregional Therapies for Primary and Secondary Hepatic Malignancies
Management of hepatic malignancies is a multidisciplinary task with the involvement of hepatologists, medical/surgical oncologists, transplant surgeons, and interventional radiologists. The patients should be ...
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Article
Hepatic imaging following intra-arterial embolotherapy
To discuss guidelines and salient imaging findings of solid tumors treated with common intra-arterial procedures used in interventional oncology.