131 Result(s)
within
Richard M. **
Pediatrics
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Article
Bradycardia with carotid system infusions of cold blood during endarterectomy
A method of local cerebral hypothermia has been used over the past nine years to mitigate the effects of cerebral ischaemia during carotid endarterectomy. Bradycardia, seen immediately after initiation of a 50...
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Article
The Role of the Adrenergic Nervous System in Regulating Systemic Arterial Pressure and Venous Return
Total cardiopulmonary bypass was achieved in closed chest dogs. Systemic venous return (SVR) was directed through a recording electromagnetic flowmeter. Systemic arterial (SAP) and central venous pressure (CVP...
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Article
Chemical Variables and New Lamps in Phototherapy
Extract: In vitro studies were undertaken to measure the effects of varying concentrations of albumin and flux on the photodecomposition of bilirubin.
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Article
The significance of transpulmonary pressure changes in children anaesthetized for cardiac surgery — analyis of respiratory mechanics
To find a practical objective parameter indicating the need for ventilatory assistance in paediatric patients after cardiac surgery measurements were made of transpulmonary pressure, pulmonary compliance and i...
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Article
ALTERATION OF HUMAN T-CELL FUNCTION AFTER THYMIC IRRADIATION
Lymphocyte responses and delayed skin reactions were studied in 12 healthy adults given thymic x-irradiation in childhood and in a 7-year-old female (K.W.) whose mother received 131I early in pregnancy. The adult...
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Article
Spontaneous Rupture of the Stomach in the Newborn: Clinical and Experimental Evaluation
Extract: Our study presents an experimental model for studying gastric rupture in the newborn. We showed that gastric rupture could be produced in eight newborn rodents and in three puppies less than 10 days o...
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Article
Bile Pigments in Humans and in Nonhuman Primates during the Perinatal Period: Composition of Meconium and Gallbladder Bile of Newborns and Adults
Extract: Meconium of human infants and rhesus monkey infants (Macaca mulatta) contained only about 0.10 of the amount of bilirubin in gallbladder bile of the same individuals.
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Article
IMMUNITY TO DIPHTHERIA IN AN URBAN POPULATION
Immunity against diphtheria (D) is poorly understood since protection is a complex interaction between host and environment and there are technical problems with existing antitoxin assays. Using a radioimmunoa...
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Article
HEPATIC INSENSITIVITY TO INSULIN IN THE NEONATAL LAMB
We have shown persistant endogenous hepatic glucose production during exogenous glucose infusion is characteristic of the newborn lamb. Glucose turnover at steady state glucose conc. falls to 0.56±1.08mg/kg/mi...
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Article
HYPOTENSIVE EFFECT OF DIAZEPAM IN SPONTANEOUSLY HYPERTENSIVE RATS (SHR)
To test if hypertension in SHR is related to exaggerated central responsiveness to environment, Diazepam (D) was chronically administered from the newborn period to adulthood. Four groups (10 each) were studie...
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Article
POSTNATAL RENAL MATURATION IN LOW BIRTH WEIGHT INFANTS
The postnatal contraction of extracellular fluid in low birth weight (LBW) infants is associated with increased solute excretion. Patterns of postnatal renal maturation were assessed with the assumption that c...
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Article
GLUCOSE DISPOSAL IN THE WELL LOW BIRTH WEIGHT (LBW) INFANT
Glucose is the primary substrate for energy during parenteral alimentation of LBW infants. Hyperglycemia may result in glucosuria and osmotic diuresis when excessive glucose is infused. Tolerance for glucose w...
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Article
AGE-DEPENDENT CHANGES IN BETA-ADRENERGIC RECEPTOR ACTIVITY OF RABBIT MYOCARDIUM
Myocardial response to beta-adrenergic stimulation, isoproterenol(ISO), was evaluated in 1 day, 1 week, 1 month and 4 months old rabbits by measuring maximal developed tension(MDT), ED50 and cyclic AMP(cAMP) prod...
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Article
SYSTOLIC TIME INTERVALS IN ATRIAL SEPTAL DEFECT
Diminished pulmonary vascular compliance (PVC) is believed to be a major determinant of the widened splitting of the second heart sound (S2) in atrial septal defect (ASD). However in association with the decrease...
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Article
Renal Functions of Low Birth Weight Infants during the First Two Months of Life
Summary: A postnatal contraction of extracellular fluid occurs in low birth weight infants. Patterns of postnatal renal maturation were assessed with the assumption that changes in body composition were mediat...
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Article
681 THYMOSIN TREATMENT OF DI GEORGE SYNDROME
A 2½-month-old infant with complete DiGeorge syndrome was treated with bovine thymosin fraction V. Initial evaluation revealed normal numbers of blood lymphocytes, 29% EAC rosettes, 41% sIg lymphocytes and no ...
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Article
255 ENZYMATIC & GAS CHROMATOGRAPHY/MASS SPECTROMETRY ANALYSIS OF CHLORAMPHENICOL IN NEWBORN INFANTS
Enzymatic and gas chromatography/mass spectrometry (GC/MS) assays for chloramphenicol (CM) were developed to assist in study of the pharmacology of CM and to establish parameters for monitoring its use. An enz...
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Article
295 SERUM THYROID STIMULATING HORMONE (TSH), THYROXINE (T4) AND TRIIODOTHYRONINE (T3) LEVELS IN THE PRE-TERM INFANT
To determine if inclusion of the healthy pre-term infant in mass neonatal screening programs would increase the number of false-positive results, the changes in serum TSH, T4 and T3 levels were studied in healthy...
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Article
157 THE CARDIOVASCULAR EFFECT OF ISOMETRIC EXERCISE IN CHILDREN
Isometric exercise (ISO) evokes profound changes in left ventricular dynamics. Scant data document the effect of ISO in children. The blood pressure (BP) heart rate (HR) and echocardiographic left ventricular ...
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Article
733 EFFECT OF PASSIVE IMMUNITY ON THE HUMORAL IMMUNE RESPONSE TO INGESTED MILK PROTEIN
Mucosal immunization to environmental antigens results in circulating and secretory antibodies (Ab). Newborns who are passively immunized are thought to have a suppressed active immune response to these antige...
