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Article
20. Major Cardiovascular Outcomes in the EXAMINE Trial According to ACE Inhibitor Use (12-OR)
Activation of the sympathetic nervous system through substance P via DPP-4 inhibition (DPP-4i) in the presence of higher dose ACE inhibition (ACEi) has led to hypothetical concerns of the cardiovascular (CV) s...
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Article
14. Glycemic control and hypoglycemia with new insulin glargine 300 U/mL in people with T1DM (EDITION 4) (80-LB (late breaking))
EDITION 4 studied the efficacy and safety of new insulin glargine (300 U/mL; Gla-300) vs glargine 100 U/mL (Gla-100) in people with T1DM. In this 6-month, multinational, multicenter, open-label study, particip...
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Article
7.4 Improved Glycemic Control Despite Reductions in Bolus Insulin Doses with Basal Insulin LY2605541 Compared with Basal Insulin Glargine in Patients with Type 1 Diabetes (915-P)
LY2605541 (LY) is a novel basal insulin analog with a prolonged duration of action. The objective of this analysis was to further explore the initial observation of a reduction in prandial insulin requirements...