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HAb18G/CD147 promotes epithelial–mesenchymal transition through TGF-β signaling and is transcriptionally regulated by Slug

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  1. Article

    Open Access

    Elevated Kir2.1/nuclear N2ICD defines a highly malignant subtype of non-WNT/SHH medulloblastomas

    Medulloblastoma (MB) is one of the most common childhood malignant brain tumors (WHO grade IV), traditionally divided into WNT, SHH, Group 3, and Group 4 subgroups based on the transcription profiles, somatic ...

    Yan-**a Wang, Haibo Wu, Yong Ren, Shengqing Lv in Signal Transduction and Targeted Therapy (2022)

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    Open Access

    UBE2S interacting with TRIM28 in the nucleus accelerates cell cycle by ubiquitination of p27 to promote hepatocellular carcinoma development

    Genomic sequencing analysis of tumors provides potential molecular therapeutic targets for precision medicine. However, identifying a key driver gene or mutation that can be used for hepatocellular carcinoma (...

    Ren-Yu Zhang, Ze-Kun Liu, Ding Wei, Yu-Le Yong in Signal Transduction and Targeted Therapy (2021)