51 Result(s)

Article

Simultaneous determination of five plant hormones in cotton leaves using QuEChERS combined with HPLC‒MS/MS

Plant hormones profoundly influence cotton growth, development, and responses to various stresses. Therefore, there is a pressing need for an efficient assay to quantify these hormones in cotton. In this groun...

Wenhao Wang, **anpeng Song, Dan Wang, Yajie Ma, Yongpan Shan… in Journal of Cotton Research (2024)

Article

FBXO32-mediated degradation of PTEN promotes lung adenocarcinoma progression

FBXO32, a member of the F-box protein family, is known to play both oncogenic and tumor-suppressive roles in different cancers. However, the functions and the molecular mechanisms regulated by FBXO32 in lung a...

Jie Wu, Ting Wen, Antonio Marzio, Dingli Song, Sisi Chen… in Cell Death & Disease (2024)

Article

Aberrant activated Notch1 promotes prostate enlargement driven by androgen signaling via disrupting mitochondrial function in mouse

The prostate is a vital accessory gonad in the mammalian male reproductive system. With the ever-increasing proportion of the population over 60 years of age worldwide, the incidence of prostate diseases, such...

**-Wen Kang, Jia-Peng He, Ying-Nan Liu, Yu Zhang… in Cellular and Molecular Life Sciences (2024)

Article

Lactobacillus rhamnosus GG ameliorates hyperuricemia in a novel model

Hyperuricemia (HUA) is a metabolic syndrome caused by abnormal purine metabolism. Although recent studies have noted a relationship between the gut microbiota and gout, whether the microbiota could ameliorate ...

Yang Fu, Yong-Song Chen, Dai-Yang **a, **ao-Dan Luo… in npj Biofilms and Microbiomes (2024)

Article

A small-molecule TNIK inhibitor targets fibrosis in preclinical and clinical models

Idiopathic pulmonary fibrosis (IPF) is an aggressive interstitial lung disease with a high mortality rate. Putative drug targets in IPF have failed to translate into effective therapies at the clinical level. ...

Feng Ren, Alex Aliper, Jian Chen, Heng Zhao, Sujata Rao… in Nature Biotechnology (2024)

Article

3α-Hydroxybufadienolides in Bufo gallbladders: structural insights and biotransformation

Bufadienolides, naturally occurring steroids primarily found in toads, have garnered attention for their pharmacological properties and ecological significance. In this study, we isolated and identified 21 buf...

Li-Jun Ruan, Zhi-Jun Song, Ren-Wang Jiang in Natural Products and Bioprospecting (2024)

Article

Unraveling the 2,3-diketo-l-gulonic acid-dependent and -independent impacts of l-ascorbic acid on somatic cell reprogramming

l-ascorbic acid (Asc) plays a pivotal role in regulating various biological processes, including somatic cell reprogramming, through multiple pathways. However, it remains unclear whether Asc regulates reprogra.....

Lining Liang, Meiai He, Yixin Zhang, Chenchen Wang, Zhaohui Qin… in Cell & Bioscience (2023)

Article

The Quartet Data Portal: integration of community-wide resources for multiomics quality control

The Quartet Data Portal facilitates community access to well-characterized reference materials, reference datasets, and related resources established based on a family of four individuals with identical twins ...

**gcheng Yang, Yaqing Liu, Jun Shang, Qiaochu Chen, Qingwang Chen… in Genome Biology (2023)

Article

Akkermansia muciniphila inhibited the periodontitis caused by Fusobacterium nucleatum

Periodontitis is the most important cause of tooth loss in adults and is closely related to various systemic diseases. Its etiologic factor is plaque biofilm, and the primary treatment modality is plaque contr...

Bingqing Song, Wenpan **an, Yan Sun, Lichen Gou, Qiang Guo… in npj Biofilms and Microbiomes (2023)

Article

Biomarkers of aging

Aging biomarkers are a combination of biological parameters to (i) assess age-related changes, (ii) track the physiological aging process, and (iii) predict the transition into a pathological status. Although ...

Hainan Bao, Jiani Cao, Mengting Chen, Min Chen, Wei Chen… in Science China Life Sciences (2023)

Article

Microbiome Structure and Mucosal Morphology of Jejunum Appendix and Colon of Rats in Health and Dysbiosis

Gut microbiota contributes to human health. Plenty of studies demonstrate that antibiotics can disrupt gut ecosystem leading to dysbiosis. Little is known about the microbial variation of appendix and its up/d...

Chenyi Shao, **aobo Song, Lili Wang, Hongying Zhang, Yinhui Liu… in Current Microbiology (2023)

Article

Correction: Human endometrium-derived stem cell improves cardiac function after myocardial ischemic injury by enhancing angiogenesis and myocardial metabolism

Xuemei Fan, Sheng He, Huifang Song, Wenjuan Yin, Jie Zhang… in Stem Cell Research & Therapy (2023)

Article

Dynamic differentiation of F4/80+ tumor-associated macrophage and its role in tumor vascularization in a syngeneic mouse model of colorectal liver metastasis

Tumor-associated macrophages (TAMs) are highly heterogeneous and play vital roles in tumor progression. Here we adopted a C57BL/6 mouse model imitating the late-stage colorectal liver metastasis (CRLM) by Mc38...

Ting Qiao, Wanli Yang, **angchuan He, ** Song, **ao Chen… in Cell Death & Disease (2023)

Article

Pyroptosis and degenerative diseases of the elderly

Pyroptosis is a recently described mechanism of programmed cell death mediated by proteins of the gasdermin family. Widely recognized signaling cascades include the classical, non-classical, caspase-3-dependen...

Jiamin Zhou, **g**g Qiu, Yuwan Song, Tiantian Liang, Sha Liu… in Cell Death & Disease (2023)

Article

Ang-(1–7)/MasR axis promotes functional recovery after spinal cord injury by regulating microglia/macrophage polarization

Inflammatory response is an essential part of secondary injury after spinal cord injury (SCI). During this period, the injury may be exacerbated through the release of a large number of inflammatory factors an...

Guang** Gu, Bin Zhu, Jie Ren, **aomeng Song, Baoyou Fan, Han Ding… in Cell & Bioscience (2023)

Article

The plastid genome of twenty-two species from Ferula, Talassia, and Soranthus: comparative analysis, phylogenetic implications, and adaptive evolution

The Ferula genus encompasses 180–185 species and is one of the largest genera in Apiaceae, with many of Ferula species possessing important medical value. The previous studies provided more information for Ferula

Huan-Huan Qin, **g Cai, Chang-Kun Liu, Ren-**u Zhou, Megan Price… in BMC Plant Biology (2023)

Article

The landscape of aging

Aging is characterized by a progressive deterioration of physiological integrity, leading to impaired functional ability and ultimately increased susceptibility to death. It is a major risk factor for chronic ...

Yusheng Cai, Wei Song, Jiaming Li, Ying **g, Chuqian Liang… in Science China Life Sciences (2022)

Article

Targeting UHRF1-SAP30-MXD4 axis for leukemia initiating cell eradication in myeloid leukemia

Aberrant self-renewal of leukemia initiation cells (LICs) drives aggressive acute myeloid leukemia (AML). Here, we report that UHRF1, an epigenetic regulator that recruits DNMT1 to methylate DNA, is highly exp...

Cheng-Long Hu, Bing-Yi Chen, Zijuan Li, Tianbiao Yang, Chun-Hui Xu… in Cell Research (2022)

Article

LncRNA Airn alleviates diabetic cardiac fibrosis by inhibiting activation of cardiac fibroblasts via a m6A-IMP2-p53 axis

Cardiac fibrosis is a leading cause of cardiac dysfunction in patients with diabetes. However, the underlying mechanisms of cardiac fibrosis remain unclear. This study aimed to investigate the role of the long...

Tingwei Peng, Mingchuan Liu, Lang Hu, Dong Guo, Di Wang, Bingchao Qi… in Biology Direct (2022)

Article

Fungal diversity notes 1512–1610: taxonomic and phylogenetic contributions on genera and species of fungal taxa

This article is the 14th in the Fungal Diversity Notes series, wherein we report 98 taxa distributed in two phyla, seven classes, 26 orders and 50 families which are described and illustrated. Taxa in this stu...

Ruvishika S. Jayawardena, Kevin D. Hyde, Song Wang, Ya-Ru Sun… in Fungal Diversity (2022)