12 Result(s)
within
Raquel López-Mejías
Science, Humanities and Social Sciences, multidisciplinary
-
Article
Open AccessExpression of osteoprotegerin and its ligands, RANKL and TRAIL, in rheumatoid arthritis
Osteoprotegerin (OPG), receptor activator of nuclear factor-ΚB ligand (RANKL) and tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) have been involved in rheumatoid arthritis (RA) pathophysiology...
-
Article
Open AccessInfluence of elevated-CRP level-related polymorphisms in non-rheumatic Caucasians on the risk of subclinical atherosclerosis and cardiovascular disease in rheumatoid arthritis
Association between elevated C-reactive protein (CRP) serum levels and subclinical atherosclerosis and cardiovascular (CV) events was described in rheumatoid arthritis (RA). CRP, HNF1A, LEPR, GCKR, NLRP3, IL1F10,...
-
Article
Open AccessInfluence of coronary artery disease and subclinical atherosclerosis related polymorphisms on the risk of atherosclerosis in rheumatoid arthritis
A genetic component influences the development of atherosclerosis in the general population and also in rheumatoid arthritis (RA). However, genetic polymorphisms associated with atherosclerosis in the general ...
-
Article
Open AccessA genome-wide association study suggests the HLA Class II region as the major susceptibility locus for IgA vasculitis
The genetic component of Immunoglobulin-A (IgA) vasculitis is still far to be elucidated. To increase the current knowledge on the genetic component of this vasculitis we performed the first genome-wide associ...
-
Article
Open AccessProtein tyrosine phosphatase non-receptor 22 and C-Src tyrosine kinase genes are down-regulated in patients with rheumatoid arthritis
Several protein tyrosine phosphatase non-receptor 22 (PTPN22) single-nucleotide polymorphisms (SNPs) have been significantly related with rheumatoid arthritis (RA) susceptibility. Nevertheless, its potential infl...
-
Article
Open AccessAssociation of circulating calprotectin with lipid profile in axial spondyloarthritis
Calprotectin (CPT) is released during inflammation, also in the context of atherosclerosis. The link between CPT and the atherosclerotic process was evaluated in several diseases. However, studies in axial spo...
-
Article
Open AccessInfluence of MUC5B gene on antisynthetase syndrome
MUC5B rs35705950 (G/T) is strongly associated with idiopathic pulmonary fibrosis (IPF) and also contributes to the risk of interstitial lung disease (ILD) in rheumatoid arthritis (RA-ILD) and chronic hypersensiti...
-
Article
Open AccessOmentin: a biomarker of cardiovascular risk in individuals with axial spondyloarthritis
Cardiovascular (CV) disease is the main cause of mortality in axial spondyloarthritis (axSpA). CV risk is enhanced by dysregulation of adipokines. Low omentin levels were associated with metabolic dysfunction ...
-
Article
Open AccessBAFF, APRIL and BAFFR on the pathogenesis of Immunoglobulin-A vasculitis
BAFF, APRIL and BAFF-R are key proteins involved in the development of B-lymphocytes and autoimmunity. Additionally, BAFF, APRIL and BAFFR polymorphisms were associated with immune-mediated conditions, being BAFF
-
Article
Open AccessRole of the IL33 and IL1RL1 pathway in the pathogenesis of Immunoglobulin A vasculitis
Cytokines signalling pathway genes are crucial factors of the genetic network underlying the pathogenesis of Immunoglobulin-A vasculitis (IgAV), an inflammatory vascular condition. An influence of the interleukin...
-
Article
Open AccessAuthor Correction: BAFF, APRIL and BAFFR on the pathogenesis of Immunoglobulin-A vasculitis
-
Article
Open AccessRole of MUC1 rs4072037 polymorphism and serum KL-6 levels in patients with antisynthetase syndrome
Mucin 1/Krebs von den Lungen-6 (KL-6) is proposed as a serum biomarker of several interstitial lung diseases (ILDs), including connective tissue disorders associated with ILD. However, it has not been studied ...
