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  1. Article

    Open Access

    Interleukin-10 polymorphisms in Spanish IgA deficiency patients: a case-control and family study

    IgA deficiency (IgAD) is the most common primary immunodeficiency in Caucasians. Genetic and environmental factors are suspected to be involved in the development of the disease. Interleukin-10 (IL-10) is a cy...

    Javier Ortiz, Miguel Fernández-Arquero, Elena Urcelay in BMC Medical Genetics (2006)

  2. Article

    Open Access

    A functional PTPN22polymorphism associated with several autoimmune diseases is not associated with IgA deficiency in the Spanish population

    The 1858C/T SNP of the PTPN22 gene has been associated with many autoimmune diseases, suggesting the existence of an inflammatory process common to all of them. We studied the association of that polymorphism wit...

    Concepción Núñez, Raquel López-Mejías, Alfonso Martínez in BMC Medical Genetics (2006)