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  1. Article

    Open Access

    Combining gene expression analysis of gastric cancer cell lines and tumor specimens to identify biomarkers for anti-HER therapies—the role of HAS2, SHB and HBEGF

    The standard treatment for patients with advanced HER2-positive gastric cancer is a combination of the antibody trastuzumab and platin-fluoropyrimidine chemotherapy. As some patients do not respond to trastuzu...

    Karolin Ebert, Ivonne Haffner, Gwen Zwingenberger, Simone Keller in BMC Cancer (2022)

  2. Article

    Open Access

    Impact of molecular subtypes on the prediction of distant recurrence in estrogen receptor (ER) positive, human epidermal growth factor receptor 2 (HER2) negative breast cancer upon five years of endocrine therapy

    Current evidence suggests that patients with Luminal A early breast cancer can skip chemotherapy or extended endocrine therapy, but immunohistochemistry-based biomarker analysis for St Gallen subty** may not...

    Mark Laible, Kerstin Hartmann, Claudia Gürtler, Tobias Anzeneder, Ralph Wirtz in BMC Cancer (2019)

  3. Article

    Open Access

    The prognostic impact of epidermal growth factor receptor in patients with metastatic gastric cancer

    The epidermal growth factor receptor (EGFR) is a potential target of anticancer therapy in gastric cancer. However, its prognostic role in metastatic gastric or gastroesophageal junction (GE) cancer has not be...

    Akin Atmaca, Dominique Werner, Claudia Pauligk, Kristina Steinmetz in BMC Cancer (2012)