34 Result(s)
within
R.R. Recker
Rheumatology
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Article
Fracture risk as determined by prospective and retrospective study designs
Both retrospectively and prospectively designed studies consistently show low bone mass and/or bone mineral content (BMC) to be risk factor for low-trauma fractures in postmenopausal women. Along with the repo...
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Article
Prevention of osteoporosis: Calcium nutrition
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Article
Revisable criteria for vertebral deformity
In order to study vertebral fractures in various study populations, we earlier prepared a database of vertebral dimensions derived from spinal radiographs of 191 normal women seen regularly over 25 years. In t...
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Article
How biased are odds ratios that are determined from redalled fracture histories?
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Article
Bone histomorphometry in long-term studies of alendronate in postmenopausal osteoporosis
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Article
Prevalence and severity of vertebral fracture: The saunders county bone quality study
Vertebral fracture prevalence and severity were analyzed by sex and age in an age-stratified proportionate sample of the enumerated population of women and men 50 years of age and older in Saunders County, Neb...
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Article
Caffeine does not affect the rate of gain in spine bone in young women
The effect of nutrition and dietary caffeine consumption and physical activity on bone gain in women during the third decade of life was determined in a longitudinal, descriptive study of 145 healthy college-a...
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Article
Influence of Activity Level on Patellar Ultrasound Transmission Velocity in Children
Optimum development of both bone mass and bone quality during childhood is crucial in prevention of osteoporosis, a condition in which fractures occur late in life. Increasing physical activity is one modalit...
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Article
Urinary Calcium in Perimenopausal Women: Normative Values
Twenty-four hour urinary calcium was measured under controlled dietary and metabolic balance conditions in 191 normal perimenopausal women at 5-year intervals, under varying conditions of estrogen status and ...
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Article
The Association of Bone Mineral Density with Vitamin D Receptor Gene Polymorphisms
A recent meta-analysis of 16 publications suggested that bone mineral density (BMD) is not associated with vitamin D receptor (VDR) gene polymorphism (VDRGP) at the 0.05 significance level when a study with g...
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Article
Association of VDR and Estrogen Receptor Genotypes with Bone Mass in Postmenopausal Caucasian Women: Different Conclusions with Different Analyses and the Implications
Much work has been done on the association between vitamin D receptor (VDR) genotypes and bone mineral density (BMD). Despite considerable effort, the results are inconsistent. While the VDR association remai...
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Article
Study Subjects and Ordinary Patients
Clinical trials of treatment agents impose strict and often necessary inclusion and exclusion criteria, while patients presenting to physicians for treatment frequently exhibit complicating features that woul...
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Article
The Impact of Lifestyle Factors on Stress Fractures in Female Army Recruits
Estimates are that stress fractures during basic training (BT) occur in as many as 14% of US female military recruits. Injuries of this type lead to morbidity ranging from minor pain to serious lifetime disab...
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Article
Gene expression studies of osteoporosis: implications for microarray research
Osteoporosis is one of the most common bone-related disorders in the elderly. It is a complex disease, and largely determined genetically. Traditional gene expression studies have shown that osteoporosis has c...
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Article
Histomorphometric evaluation of daily and intermittent oral ibandronate in women with postmenopausal osteoporosis: results from the BONE study
The bisphosphonate ibandronate, administered either daily or intermittently with an extended between-dose interval of >2 months, has been shown to reduce significantly the incidence of vertebral fractures, to ...
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Daily and intermittent oral ibandronate normalize bone turnover and provide significant reduction in vertebral fracture risk: results from the BONE study
Increasing evidence suggests that a high rate of bone turnover is associated with low bone mineral density (BMD) and is strongly linked to fracture risk. Measurement of biochemical markers of bone turnover is ...
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Article
A whole genome linkage scan for QTLs underlying peak bone mineral density
We conducted a whole genome linkage scan for quantitative trait loci (QTLs) underlying peak bone mineral density (PBMD). Our efforts identified several potential genomic regions for PBMD and highlighted the im...
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Article
Monthly dosing of 75 mg risedronate on 2 consecutive days a month: efficacy and safety results
Postmenopausal women with osteoporosis received 75 mg risedronate on two consecutive days each month or 5 mg daily for 12 months. Changes in bone mineral density and bone turnover markers were similar between ...
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Article
Comparison of whole genome linkage scans in premenopausal and postmenopausal women: no bone-loss-specific QTLs were implicated
This study was conducted to investigate if there exist bone-loss-specific quantitative trait loci (QTLs) for females. Genome-wide linkage scans were conducted in total, premenopausal, and postmenopausal women,...
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Article
Association analyses of vitamin D-binding protein gene with compression strength index variation in Caucasian nuclear families
This study was conducted to test whether there exists an association between vitamin D-binding protein (DBP) gene and compression strength index (CSI) phenotype. Candidate gene association analyses were conducted...
