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Article
Clinical evidence for immunomodulation induced by high-dose melphalan and autologous blood stem cell transplantation as cause for complete clinical remission of multiple myeloma-associated cryoglobulin-vasculitis
We present a case report of a patient with cryoglobulin-vasculitis caused by multiple myeloma in Durie/Salmon stage I refractory to conventional therapy modalities treated with high-dose chemotherapy followed ...
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Article
Clinical outcome of Schönlein-Henoch purpura nephritis in children
We studied the long-term outcome of 64 children with biopsy-proven Schönlein-Henoch purpura (SHP) nephritis over 1–23 years of follow-up. Overall renal survival 10 years after onset was 73%. Multivariate logis...
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Article
X-chromosome methylation ratios as indicators of chromosomal activity: Evidence of intraindividual divergencies among tissues of different embryonal origin
To test whether the differentiation events that lead to the embryonal layers and their derived organs produce divergent X-chromosome activation ratios among the different tissues, the X-chromosome activation r...
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Article
Tumor induction and prophylaxis following different forms of intestinal urinary diversion in a rat model
Eighty Wistar rats were randomized into two groups. In group 1 vesicosigmoidostomy with proximal colostomy was performed, in group 2, vesicosigmoidostomy. The total tumor incidence did not differ significantly...
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Chapter and Conference Paper
In Situ Expression of Cytokines in Renal Cell Carcinoma
Cytokines play an important role in the induction and maintenance of specific and nonspecific defense mechanisms by immunocompetent mononuclear cells in malignant tumors, including renal cell carcinoma (RCC) [...
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Chapter and Conference Paper
High Prevalence of Helicobacter pylori-Induced Gastritis in China: Results of a Screening Study in 194 Adolescents
Helicobacter pylori (HP) infection has been reported in populations all over the world. Whereas the direct source of infection is still unknown, there is increasing evidence that HP is spread via a...
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Article
The nephronophthisis complex: clinical and genetic aspects
Familial juvenile nephronophthisis (NPH) and medullary cystic disease (MCD) are hereditary forms of early-onset chronic renal failure caused by the bilateral formation of cysts at the corticomedullary junction...
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Article
Pathology of the human mesangium in situ
Mesangial cells play an important role in the development and progression of human glomerular disease. This article summarizes some important aspects of mesangial properties and behaviour in situ. Intrinsic me...
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Article
Long-term effects of ovariectomy on pituitary-adrenal axis and specific antibody response in rats
The effects of ovariectomy on morphologically demonstrable characteristics of lymphoid tissue, pituitary, and adrenal glands as well as on plasma ACTH and corticosterone levels and humoral immunity of female L...
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Article
Nucleolar organizer regions in myogenic stromal tumours of the stomach
Silver staining of nucleolar organizer regions (AgNOR) was studied in 26 primary benign and malignant gastric stromal tumours of myogenic origin. The absolute number of AgNOR per nucleus and the size of AgNOR ...
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Chapter
Pathology of the Human Juxtaglomerular Apparatus
To our current knowledge, there are no fundamental differences between humans and other mammalian species either in the histology of the JGA or in the ultrastructure of the granulated renin-producing cells. Co...
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Article
The juxtaglomerular apparatus in Bartter's syndrome and related tubulopathies
A comparative immunocytochemical and electron microscopic study was performed on renal biopsies from two children with classical Bartter's syndrome (BS) and three children with a recently described variant, th...
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Article
Synergistic effects of diabetes mellitus and renovascular hypertension on the rat heart - stereological investigations on papillary muscles
The effects of combined renovascular hypertension and diabetes mellitus on the rat heart were investigated in order to detect possible synergistic effects of the two conditions. Hypertensive diabetic and hyper...
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Article
Influence of hypertension on serum concentration of type IV collagen antigens in streptozotocin-diabetic and non-diabetic rats
The serum concentration of 7S collagen was measured radioimmunologically as a marker of basement membrane type IV collagen synthesis in diabetic and nondiabetic rats with Goldblatt hypertension. In non-diabeti...
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Article
Anti-glomerular basement membrane antibody-mediated glomerulonephritis due to glue sniffing
A 16-year-old girl developed rapidly progressive glomerulonephritis and renal failure. The disease was associated with high titres of antiglomerular basement membrane antibodies in serum, linear deposits of im...
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Article
The fate of prorenin during granulopoiesis in epithelioid cells
Comparative immunocytochemical experiments with antisera directed against renin and three synthetical peptides (Pro 1, Pro 2 A and Pro 3) covering almost the entire span of human renin prosegment were performe...
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Article
Generalized amyloidosis secondary to xanthogranulomatous pyelonephritis
Unilateral nephrectomy in an 8-year-old male with chronic renal failure and urosepsis revealed a combined histologic lesion of xanthogranulomatous pyelonephritis and amyloidosis. Amyloid deposits were found al...
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Article
Acquired cystic kidney disease —a possible pitfall in genetic counseling
A case of a 24-year-old pregnant woman on dialysis who asked for genetic counseling is reported. Differentiation between nonheritable acquired cystic kidneys and autosomal dominant polycystic kidney disease wi...
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Article
Co-expression of cytokeratin and vimentin intermediate-sized filaments in renal cell carcinomas
The expression of intermediate-sized filaments (IF) was examined by immunocytochemical methods in 40 primary renal cell carcinomas and compared with the IF distribution in the normal adult human kidney. All tu...
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Chapter and Conference Paper
Problems in Spleen Autotransplantation: Comparative Study of Types of Implantation in Animal Experiments
Spleen-preserving operations, either for maintenance of the whole organ or for partial resection, have absolute priority over autotransplantation when suitably indicated. Experimental examinations have shown t...