23 Result(s)
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Article
Clinical evidence for immunomodulation induced by high-dose melphalan and autologous blood stem cell transplantation as cause for complete clinical remission of multiple myeloma-associated cryoglobulin-vasculitis
We present a case report of a patient with cryoglobulin-vasculitis caused by multiple myeloma in Durie/Salmon stage I refractory to conventional therapy modalities treated with high-dose chemotherapy followed ...
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Article
Clinical outcome of Schönlein-Henoch purpura nephritis in children
We studied the long-term outcome of 64 children with biopsy-proven Schönlein-Henoch purpura (SHP) nephritis over 1–23 years of follow-up. Overall renal survival 10 years after onset was 73%. Multivariate logis...
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Article
Tumor induction and prophylaxis following different forms of intestinal urinary diversion in a rat model
Eighty Wistar rats were randomized into two groups. In group 1 vesicosigmoidostomy with proximal colostomy was performed, in group 2, vesicosigmoidostomy. The total tumor incidence did not differ significantly...
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Chapter and Conference Paper
In Situ Expression of Cytokines in Renal Cell Carcinoma
Cytokines play an important role in the induction and maintenance of specific and nonspecific defense mechanisms by immunocompetent mononuclear cells in malignant tumors, including renal cell carcinoma (RCC) [...
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Article
Long-term effects of ovariectomy on pituitary-adrenal axis and specific antibody response in rats
The effects of ovariectomy on morphologically demonstrable characteristics of lymphoid tissue, pituitary, and adrenal glands as well as on plasma ACTH and corticosterone levels and humoral immunity of female L...
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Article
Nucleolar organizer regions in myogenic stromal tumours of the stomach
Silver staining of nucleolar organizer regions (AgNOR) was studied in 26 primary benign and malignant gastric stromal tumours of myogenic origin. The absolute number of AgNOR per nucleus and the size of AgNOR ...
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Chapter
Pathology of the Human Juxtaglomerular Apparatus
To our current knowledge, there are no fundamental differences between humans and other mammalian species either in the histology of the JGA or in the ultrastructure of the granulated renin-producing cells. Co...
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Article
The juxtaglomerular apparatus in Bartter's syndrome and related tubulopathies
A comparative immunocytochemical and electron microscopic study was performed on renal biopsies from two children with classical Bartter's syndrome (BS) and three children with a recently described variant, th...
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Article
Synergistic effects of diabetes mellitus and renovascular hypertension on the rat heart - stereological investigations on papillary muscles
The effects of combined renovascular hypertension and diabetes mellitus on the rat heart were investigated in order to detect possible synergistic effects of the two conditions. Hypertensive diabetic and hyper...
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Article
Influence of hypertension on serum concentration of type IV collagen antigens in streptozotocin-diabetic and non-diabetic rats
The serum concentration of 7S collagen was measured radioimmunologically as a marker of basement membrane type IV collagen synthesis in diabetic and nondiabetic rats with Goldblatt hypertension. In non-diabeti...
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Article
Anti-glomerular basement membrane antibody-mediated glomerulonephritis due to glue sniffing
A 16-year-old girl developed rapidly progressive glomerulonephritis and renal failure. The disease was associated with high titres of antiglomerular basement membrane antibodies in serum, linear deposits of im...
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Article
Generalized amyloidosis secondary to xanthogranulomatous pyelonephritis
Unilateral nephrectomy in an 8-year-old male with chronic renal failure and urosepsis revealed a combined histologic lesion of xanthogranulomatous pyelonephritis and amyloidosis. Amyloid deposits were found al...
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Article
Co-expression of cytokeratin and vimentin intermediate-sized filaments in renal cell carcinomas
The expression of intermediate-sized filaments (IF) was examined by immunocytochemical methods in 40 primary renal cell carcinomas and compared with the IF distribution in the normal adult human kidney. All tu...
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Chapter and Conference Paper
Problems in Spleen Autotransplantation: Comparative Study of Types of Implantation in Animal Experiments
Spleen-preserving operations, either for maintenance of the whole organ or for partial resection, have absolute priority over autotransplantation when suitably indicated. Experimental examinations have shown t...
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Article
Mesangial alterations in steroid-responsive minimal change nephrotic syndrome
Renal biopsies from 25 children with steroid-sensitive minimal change nephrotic syndrome were evaluated retrospectively to determine whether there is any relation between the morphological changes and the freq...
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Article
Adolescent cystinosis: Renal function and morphology
Morphological and functional investigations of the kidney were performed in an adolescent with cystinosis. The late onset and the gradual development of moderate complex tubular dysfunction was documented. Whe...
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Chapter and Conference Paper
The Nephronophthisis Complex; a Clinicopathologic Study
In 1951 Fanconi and co-workers described seven children from two families suffering from progressive renal insufficiency due to a chronic tubulointerstitial nephropathy. The disorder was termed “familial juven...
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Chapter and Conference Paper
Idiopathic Nephrotic Syndrome Associated with Focal Segmental Glomerulosclerosis
In the last ten years focal segmental glomerulosclerosis (FSGS) has stimulated the interest of many pediatric nephrologists as a main glomerular lesion associated with the idiopathic nephrotic syndrome (NS) le...
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Article
The nephronophthisis complex
The clinical and morphological findings are described in 27 children with nephronophthisis. Seventeen children were considered as sporadic cases. In 10 familial cases the presumed mode of inheritance was autos...
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Chapter
Nephrolithiasis in Dialysed Patients — Evidence for a Peculiar Type of Matrix Stones with Ca-Oxalate Inclusions
Recently it has been recognized by Bommer1 and Caralps2 that nephrolithiasis may arise de novo in patients on maintenance hemodialysis. Such stones were shown to consist of a protein matrix with amyloid-like micr...
