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Article
Evaluation of muscle oxidative potential by 31P-MRS during incremental exercise in old and young humans
The purpose of this study was to compare muscle oxidative capacity between moderately active young and old humans by measuring intracellular threshold (IT) during exercise with 31P-magnetic resonance spectroscop...
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Article
Similar long-term cardiovascular effects of propofol or isoflurane anesthesia during ischemia/ reperfusion in dogs
To compare the long-term functional and metabolic effects of propofol or isoflurane general anesthesia in a canine model of ischemia/reperfusion.
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Article
Open AccessThe effect of forearm posture on wrist flexion in computer workers with chronic upper extremity musculoskeletal disorders
Occupational computer use has been associated with upper extremity musculoskeletal disorders (UEMSDs), but the etiology and pathophysiology of some of these disorders are poorly understood. Various theories at...
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Article
Changes in Cerebral Oxygen Consumption and High-Energy Phosphates During Early Recovery in Hypoxic-Ischemic Piglets: A Combined Near-Infrared and Magnetic Resonance Spectroscopy Study
Near-infrared spectroscopy (NIRS) offers the ability to assess brain function at the bedside of critically ill neonates. Our group previously demonstrated a persistent reduction in the cerebral metabolic rate ...
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Article
Females Follow a More “Compact” Early Human Brain Development Model Than Males. A Case-Control Study of Preterm Neonates
The pattern of sexual differentiation of the human brain is not well understood, particularly at the early stages of development when intense growth and multiple maturational phenomena overlap and interrelate....
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Article
Open AccessMRI-identified abnormalities and wrist range of motion in asymptomatic versus symptomatic computer users
Previous work has shown an association between restricted wrist range of motion (ROM) and upper extremity musculoskeletal disorders in computer users. We compared the prevalence of MRI-identified wrist abnorma...
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Article
Open AccessMyocardial fibrosis is not associated with reduced quality of life in patients with dilated or hypertrophic cardiomyopathy
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Article
Imaging Tumor Growth Non-invasively Using Expression of MagA or Modified Ferritin Subunits to Augment Intracellular Contrast for Repetitive MRI
The bacterial gene MagA imparts magnetic properties to mammalian cells and provides a basis for cell tracking by magnetic resonance imaging (MRI). In a mouse model of tumor growth from transplanted cells, we used...
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Article
The influence on sarcopenia of muscle quality and quantity derived from magnetic resonance imaging and neuromuscular properties
The relative contributions of intrinsic and extrinsic neuromuscular factors on sarcopenia are poorly understood. The associations among age-related declines of strength, muscle mass, and muscle quality in resp...
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Chapter
Forming Magnetosome-Like Nanoparticles in Mammalian Cells for Molecular MRI
To identify molecular activities that define the early stages of disease progression, there is a critical need to noninvasively image these processes. For this, the magnetosome is an ideal structure by which c...
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Article
Open AccessMRI T2 and T1ρ relaxation in patients at risk for knee osteoarthritis: a systematic review and meta-analysis
Magnetic resonance imaging (MRI) T2 and T1ρ relaxation are increasingly being proposed as imaging biomarkers potentially capable of detecting biochemical changes in articular cartilage before structural change...
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Article
Open AccessAssessment of a novel 32-channel phased array for cardiovascular hybrid PET/MRI imaging: MRI performance
Cardiovascular imaging using hybrid positron emission tomography (PET) and magnetic resonance imaging (MRI) requires a radio frequency phased array resonator capable of high acceleration factors in order to ac...
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Article
Open AccessEvaluation of 511 keV photon attenuation by a novel 32-channel phased array prospectively designed for cardiovascular hybrid PET/MRI imaging
Simultaneous cardiovascular imaging with positron emission tomography (PET) and magnetic resonance imaging (MRI) requires tools such as radio frequency (RF) phased arrays to achieve high temporal and spatial r...
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Article
The Effect of Registration on Voxel-Wise Tofts Model Parameters and Uncertainties from DCE-MRI of Early-Stage Breast Cancer Patients Using 3DSlicer
We quantitatively investigate the influence of image registration, using open-source software (3DSlicer), on kinetic analysis (Tofts model) of dynamic contrast enhanced MRI of early-stage breast cancer patient...
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Article
Open AccessImproved PET/MRI accuracy by use of static transmission source in empirically derived hardware attenuation correction
Accurate quantification of radioactivity, measured by an integrated positron emission tomography (PET) and magnetic resonance imaging (MRI) system, is still a challenge. One aspect of such a challenge is to co...