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    Article

    Immunotherapy in allogeneic hematopoietic stem cell transplantation – not just a case for effector cells

    The concept that in allogeneic hematopoietic stem cell transplantation (alloHSCT) the immune system plays a prominent role in the control of leukemic disease is supported by the clinical observation that immun...

    A Troeger, R Meisel, T Moritz, D Dilloo in Bone Marrow Transplantation (2005)

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    Article

    Diagnostic and therapeutic implications of neurological complications following paediatric haematopoietic stem cell transplantation

    Neurological complications are a relevant cause of morbidity and mortality after haematopoietic stem cell transplantation (SCT). We retrospectively analysed neurological complications of 165 paediatric patient...

    C Weber, J Schaper, D Tibussek, O Adams, C R MacKenzie in Bone Marrow Transplantation (2008)

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    Article

    Human but not murine multipotent mesenchymal stromal cells exhibit broad-spectrum antimicrobial effector function mediated by indoleamine 2,3-dioxygenase

    Human multipotent mesenchymal stromal cells (MSCs) exhibit multilineage differentiation potential, support hematopoiesis, and inhibit proliferation and effector function of various immune cells. On the basis o...

    R Meisel, S Brockers, K Heseler, Ö Degistirici, H Bülle, C Woite, S Stuhlsatz in Leukemia (2011)

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    Article

    Long-term follow-up of children conditioned with Treosulfan: German and Austrian experience

    We report the long-term follow-up of children transplanted with Treosulfan (TREO)-based conditioning in Germany and Austria. Nine centres reported a total of 109 transplantations. Patients were stratified acco...

    R Beier, A Schulz, M Hönig, M Eyrich, P-G Schlegel, W Holter in Bone Marrow Transplantation (2013)

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    Article

    Allo-SCT using BU, CY and melphalan for children with AML in second CR

    Based on the results from the AML-BFM 98 trial, hematopoietic SCT (HSCT) is recommended for children with AML in second CR only. Here, we retrospectively analyze interphase data of children who underwent HSCT ...

    R Beier, M H Albert, P Bader, A Borkhardt, U Creutzig in Bone Marrow Transplantation (2013)

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    Article

    Mesenchymal stromal cells in the antimicrobial host response of hematopoietic stem cell recipients with graft-versus-host disease—friends or foes?

    Mesenchymal stromal cells (MSCs) are multipotent cells, which exhibit broad immunosuppressive activities. Moreover, they may be administered irrespectively of human leukocyte antigen (HLA) compatibility, witho...

    A Balan, G Lucchini, S Schmidt, A Schneider, L Tramsen, S Kuçi, R Meisel in Leukemia (2014)

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    Article

    Donor choice in haploidentical stem cell transplantation: fetal microchimerism is associated with better outcome in pediatric leukemia patients

    A Kruchen, T Stahl, F Gieseke, T M C Binder, Z Özcan in Bone Marrow Transplantation (2015)

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    Article

    Control of AC133/CD133 and impact on human hematopoietic progenitor cells through nucleolin

    AC133 is a prominent surface marker of CD34+ and CD34− hematopoietic stem/progenitor cell (HSPC) subsets. AC133+ HSPCs contain high progenitor cell activity and are capable of hematopoietic reconstitution. Fur...

    S Bhatia, S Reister, C Mahotka, R Meisel, A Borkhardt, E Grinstein in Leukemia (2015)