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    Genetic and pharmacological antagonism of NK1 receptor prevents opiate abuse potential

    Development of an efficacious, non-addicting analgesic has been challenging. Discovery of novel mechanisms underlying addiction may present a solution. Here we target the neurokinin system, which is involved i...

    A J Sandweiss, M I McIntosh, A Moutal, R Davidson-Knapp, J Hu… in Molecular Psychiatry (2018)