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  1. Article

    Open Access

    Tumour hypoxia determines the potential of combining mTOR and autophagy inhibitors to treat mammary tumours

    Hypoxia can activate autophagy, a self-digest adaptive process that maintains cell turnover. Mammalian target of rapamycin (mTOR) inhibitors are used to treat cancer but also stimulate autophagy.

    E Seront, R Boidot, C Bouzin, O Karroum, B F Jordan, B Gallez in British Journal of Cancer (2013)

  2. Article

    Open Access

    Gene expression profile and response to trastuzumab–docetaxel-based treatment in breast carcinoma

    Resistance to trastuzumab is often observed in women with human epidermal growth factor receptor 2 (HER2)-positive breast cancer and has been shown to involve multiple potential mechanisms. We examined the abi...

    F Végran, R Boidot, B Coudert, P Fumoleau, L Arnould in British Journal of Cancer (2009)