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2 Result(s)
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Quanxue Li
Biomedicine, general
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Article
Open AccessmiR-181a plays the tumor-suppressor role in chronic myeloid leukemia CD34 + cells partially via SERPINE1
The formation of the BCR-ABL fusion gene drives human chronic myeloid leukemia (CML). The last 2 decades have witnessed that specific tyrosine kinase inhibitors (TKIs, e.g., imatinib mesylate, IM) against ABL1 im...
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Article
Open AccessDRAP: a toolbox for drug response analysis and visualization tailored for preclinical drug testing on patient-derived xenograft models
One of the key reasons for the high failure rate of new agents and low therapeutic benefit of approved treatments is the lack of preclinical models that mirror the biology of human tumors. At present, the opti...
