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Article
Open AccessEffect of autophagy on aging-related changes in orthodontic tooth movement in rats
The number of adult orthodontic patients is increasing, and studies have shown that autophagy is involved in regulating orthodontic tooth movement and plays an important role in aging-related changes. Therefor...
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Article
Open AccessIsolation and anti-neuroinflammation activity of sesquiterpenoids from Artemisia argyi: computational simulation and experimental verification
Artemisia argyi is a traditional herbal medicine belonging to the genus Artemisia that plays an important role in suppressing inflammation. However, the chemical constituents and underlying mechanisms of its ther...
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Article
Open AccessAsymptotic stability and bifurcations of a perturbed McMillan map
This paper presents various bifurcations of the McMillan map under perturbations of its coefficients, such as period-doubling, pitchfork, and hysteresis bifurcation. The associated existence regions are locate...
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Article
Open AccessHuman umbilical cord mesenchymal stem cells improve uterine incision healing after cesarean delivery in rats by modulating the TGF-β/Smad signaling pathway
Although human umbilical cord-derived mesenchymal stem cells (HU-MSCs) have attracted increasing attention because of their pivotal functions in the process of wound healing, the underlying molecular mechanism...
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Article
Open AccessEntire expressed peripheral blood transcriptome in pediatric severe malarial anemia
This study on severe malarial anemia (SMA: Hb < 6.0 g/dL), a leading global cause of childhood morbidity and mortality, compares the entire expressed whole blood host transcriptome between Kenyan children (3-4...
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Article
Open AccessSecretome profiling reveals acute changes in oxidative stress, brain homeostasis, and coagulation following short-duration spaceflight
As spaceflight becomes more common with commercial crews, blood-based measures of crew health can guide both astronaut biomedicine and countermeasures. By profiling plasma proteins, metabolites, and extracellu...
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Article
Open AccessNoninvasive pressure-strain loop quantitative assessment of left ventricular function in anemic preterm infants with different modes of respiratory support
To investigate noninvasive pressure-strain loop (PSL) combined with two-dimensional speck tracking imaging and left ventricular pressure measurement in the evaluation of cardiac function changes in anemia of p...
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Article
A nomogram model for predicting the efficacy of cyclosporine in patients with pure red cell aplasia
Pure red cell aplasia (PRCA) is a rare bone marrow disorder characterized by a severe reduction or absence of erythroid precursor cells, without affecting granulocytes and megakaryocytes. Immunosuppressive the...
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Article
Advances in understanding the mechanisms of organ abscission in vivo and in vitro plants
Plant organ abscission is a fundamental biological process. and is a stress and evolutionary mechanism formed to adapt to environmental changes due to external signal stimulation or age development. Flower, le...
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Article
High-resolution modelling identifies the Bering Strait’s role in amplified Arctic warming
The Arctic region has warmed nearly four times faster than the global average since 1979, with far-reaching global implications. However, model projections of Arctic warming rates are uncertain and one key com...
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Article
Cauliflower-like Ni3S2 foam for ultrastable oxygen evolution electrocatalysis in alkaline seawater
It is of great importance to design and develop electrocatalysts that are both long-lasting and efficient for seawater oxidation. Herein, a three-dimensional porous cauliflower-like Ni3S2 foam on Ni foam (Ni3S2 f...
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Article
Open AccessAs1411-modified liposomes to enhance drug utilization and augment the anti-tumor efficacy
The utilization of liposomes in drug delivery has garnered significant attention due to their efficient drug loading capacity and excellent biocompatibility, rendering them a promising platform for tumor thera...
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Article
Toughening modification on self-reinforced composite of the rPET fibers/rPETG
In this work, self-reinforced composite of recycled polyester (rPET) fibers/recycled poly (ethylene terephthalateco-1,4-cylclohexy-lenedimethylene terephthalate) (rPETG) was prepared by internal mixing and mol...
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Article
Entomopathogenic fungi-based silver nanoparticles: a potential substitute of synthetic insecticides to counter behavioral and physiological immunity in Aedes aegypti mosquito (Diptera: Culicidae)
Excessive use of synthetic insecticides has resulted in environmental contamination and adverse effects on humans and other non-target organisms. Entomopathogenic fungi offer eco-friendly alternatives; however...
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Article
A new hip fracture risk index derived from FEA-computed proximal femur fracture loads and energies-to-failure
Hip fracture risk assessment is an important but challenging task. Quantitative CT-based patient-specific finite element (FE) analysis (FEA) incorporates bone geometry and bone density in the proximal femur. W...
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Article
HOXB9 promotes laryngeal squamous cell carcinoma progression by upregulating MMP12
Transcriptional factor HOXB9, a part of the HOX gene family, plays a crucial role in the development of diverse cancer types. This study aimed to elucidate the regulatory mechanism of HOXB9 on the proliferation a...
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Article
Interface construction and properties of polyester fibers reinforced acrylonitrile-butadiene rubber coordination composites
Polyester (PET) fibers are widely used in tire skeleton materials, conveyor belt and other fields for theirs high strength, good elasticity and other advantages. In this work, PET fibers were firstly modified ...
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Article
Image-based artificial intelligence for the prediction of pathological complete response to neoadjuvant chemoradiotherapy in patients with rectal cancer: a systematic review and meta-analysis
Artificial intelligence (AI) holds enormous potential for noninvasively identifying patients with rectal cancer who could achieve pathological complete response (pCR) following neoadjuvant chemoradiotherapy (n...
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Article
The effect of strain rate on the tensile properties of nitrile butadiene rubber with dual crosslinked networks
Requirements for the material with high tensile strength and elongation at break are proposed with the development of soft and stretchable electronics. The nitrile butadiene rubber (NBR) crosslinked by coordin...
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Article
Open AccessThe analysis on groundwater storage variations from GRACE/GRACE-FO in recent 20 years driven by influencing factors and prediction in Shandong Province, China
Monitoring and predicting the regional groundwater storage (GWS) fluctuation is an essential support for effectively managing water resources. Therefore, taking Shandong Province as an example, the data from G...
