38 Result(s)

Article

A cocktail nanovaccine targeting key entry glycoproteins elicits high neutralizing antibody levels against EBV infection

Epstein-Barr virus (EBV) infects more than 95% of adults worldwide and is closely associated with various malignancies. Considering the complex life cycle of EBV, develo** vaccines targeting key entry glycop...

Ling Zhong, Wanlin Zhang, Hong Liu, **nyu Zhang, Zeyu Yang… in Nature Communications (2024)

Article

Integrated optimization modelling framework for low-carbon and green regional transitions through resource-based industrial symbiosis

The development and utilization of bulk resources provide the basic material needs for industrial systems. However, most current resource utilization patterns are unsustainable, with low efficiencies and high ...

**n **e, Hang Fu, Qisheng Zhu, Shanying Hu in Nature Communications (2024)

Article

Encoding ordered structural complexity to covalent organic frameworks

Installing different chemical entities onto crystalline frameworks with well-defined spatial distributions represents a viable approach to achieve ordered and complex synthetic materials. Herein, a covalent or...

Lei Wei, **nyue Hai, Tongtong Xu, Zidi Wang, Wentao Jiang… in Nature Communications (2024)

Article

Trans-lesion synthesis and mismatch repair pathway crosstalk defines chemoresistance and hypermutation mechanisms in glioblastoma

Almost all Glioblastoma (GBM) are either intrinsically resistant to the chemotherapeutical drug temozolomide (TMZ) or acquire therapy-induced mutations that cause chemoresistance and recurrence. The genome mai...

**ng Cheng, **g An, Jitong Lou, Qisheng Gu, Weimin Ding… in Nature Communications (2024)

Article

Homogenizing out-of-plane cation composition in perovskite solar cells

Perovskite solar cells with the formula FA_1−xCs_xPbI₃, where FA is formamidinium, provide an attractive option for integrating high efficiency, durable stability and compatibility with scaled-up fabrication. Despi...

Zheng Liang, Yong Zhang, Huifen Xu, Wen**g Chen, Boyuan Liu, Jiyao Zhang… in Nature (2023)

Article

Pb-rich Cu grain boundary sites for selective CO-to-n-propanol electroconversion

Electrochemical carbon monoxide (CO) reduction to high-energy-density fuels provides a potential way for chemical production and intermittent energy storage. As a valuable C₃ species, n-propanol still suffers fro...

Wenzhe Niu, Zheng Chen, Wen Guo, Wei Mao, Yi Liu, Yunna Guo… in Nature Communications (2023)

Article

Shift of human pathogen community composition and their potential human health risk after supply suspension in tap water

Water supply suspension–restoration can occur frequently due to the overhauling of civil infrastructure in develo** countries and the shutdown of commercial buildings during the pandemic. For comprehensive i...

Shengnan Liu, Qisheng Li, Ruiming Jiang, Peng Liu, Xu-**ang Zhang in Scientific Reports (2023)

Article

Retraction Note: Production of viable chicken by allogeneic transplantation of primordial germ cells induced from somatic cells

Ruifeng Zhao, Qisheng Zuo, **a Yuan, Kai **, **g **, Ying Ding… in Nature Communications (2023)

Article

PDLIM1 inhibits cell migration and invasion in diabetic retinopathy via negatively regulating Wnt3a

The injury of vascular endothelial cells is a crucial factor in the development of diabetic retinopathy (DR). PDLIM1 (a member of the PDZ and LIM protein family) has been reported to exert an essential functio...

Pinxue **e, Qisheng You, Jiang Zhu, Wuxiang **e, ** Wei, Siquan Zhu… in Scientific Reports (2023)

Article

Identidication of novel biomarkers in non-small cell lung cancer using machine learning

Lung cancer is one of the leading causes of cancer-related deaths worldwide, and non-small cell lung cancer (NSCLC) accounts for a large proportion of lung cancer cases, with few diagnostic and therapeutic tar...

Fangwei Wang, Qisheng Su, Chaoqian Li in Scientific Reports (2022)

Article

Inhibition of UBA6 by inosine augments tumour immunogenicity and responses

Anti-cancer immunity and response to immune therapy is influenced by the metabolic states of the tumours. Immune checkpoint blockade therapy (ICB) is known to involve metabolic adaptation, however, the mechani...

Lei Zhang, Li Jiang, Liang Yu, Qin Li, **angjun Tian, **gquan He… in Nature Communications (2022)

Article

Toward a BT.2020 green emitter through a combined multiple resonance effect and multi-lock strategy

Color-saturated green-emitting molecules with high Commission Internationale de L’Eclairage (CIE) y values have great potential applications for displays and imaging. Here, we linked the outer phenyl groups in...

Junyuan Liu, Yunhui Zhu, Taiju Tsuboi, Chao Deng, Weiwei Lou… in Nature Communications (2022)

Article

Targeting retinoic acid receptor alpha-corepressor interaction activates chaperone-mediated autophagy and protects against retinal degeneration

Chaperone-mediated autophagy activity, essential in the cellular defense against proteotoxicity, declines with age, and preventing this decline in experimental genetic models has proven beneficial. Here, we ha...

Raquel Gomez-Sintes, Qisheng **n, Juan Ignacio Jimenez-Loygorri… in Nature Communications (2022)

Article

Insights into the inhibition of type I-F CRISPR-Cas system by a multifunctional anti-CRISPR protein AcrIF24

CRISPR-Cas systems are prokaryotic adaptive immune systems and phages use anti-CRISPR proteins (Acrs) to counteract these systems. Here, we report the structures of AcrIF24 and its complex with the crRNA-guide...

Lingguang Yang, Laixing Zhang, Peipei Yin, Hao Ding, Yu **ao… in Nature Communications (2022)

Article

RETRACTED ARTICLE: Production of viable chicken by allogeneic transplantation of primordial germ cells induced from somatic cells

The allogeneic transplantation of primordial germ cells (PGCs) derived from somatic cells overcomes the limitation of avian cloning. Here, we transdifferentiate chicken embryo fibroblasts (CEFs) from black fea...

Ruifeng Zhao, Qisheng Zuo, **a Yuan, Kai **, **g **, Ying Ding… in Nature Communications (2021)

Article

A SARS-CoV-2 neutralizing antibody with extensive Spike binding coverage and modified for optimal therapeutic outcomes

COVID-19 pandemic caused by SARS-CoV-2 constitutes a global public health crisis with enormous economic consequences. Monoclonal antibodies against SARS-CoV-2 can provide an important treatment option to fight...

Yu Guo, Lisu Huang, Guangshun Zhang, Yanfeng Yao, He Zhou… in Nature Communications (2021)

Article

Crystal structure of steroid reductase SRD5A reveals conserved steroid reduction mechanism

Steroid hormones are essential in stress response, immune system regulation, and reproduction in mammals. Steroids with 3-oxo-Δ⁴ structure, such as testosterone or progesterone, are catalyzed by steroid 5α-reduct...

Yufei Han, Qian Zhuang, Bo Sun, Wen** Lv, Sheng Wang… in Nature Communications (2021)

Article

Both Boceprevir and GC376 efficaciously inhibit SARS-CoV-2 by targeting its main protease

COVID-19 was declared a pandemic on March 11 by WHO, due to its great threat to global public health. The coronavirus main protease (M^pro, also called 3CLpro) is essential for processing and maturation of the vir...

Lifeng Fu, Fei Ye, Yong Feng, Feng Yu, Qisheng Wang, Yan Wu… in Nature Communications (2020)

Article

Variation among 532 genomes unveils the origin and evolutionary history of a global insect herbivore

The diamondback moth, Plutella xylostella is a cosmopolitan pest that has evolved resistance to all classes of insecticide, and costs the world economy an estimated US $4-5 billion annually. We analyse patterns o...

Minsheng You, Fushi Ke, Shijun You, Zhangyan Wu, Qingfeng Liu… in Nature Communications (2020)