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    Article

    Perioperative complications of middle cerebral artery occlusion in rats alleviated by human umbilical cord mesenchymal stem cells

    For acute ischemic stroke treatment, the limitations of treatment methods and the high incidence of perioperative complications seriously affect the survival rate and postoperative recovery of patients. Human ...

    Liang Liu, Yating Luo, Tao Xu, Qisheng Tang in Naunyn-Schmiedeberg's Archives of Pharmaco… (2024)

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    Open Access

    Mas receptor activation facilitates innate hematoma resolution and neurological recovery after hemorrhagic stroke in mice

    Intracerebral hemorrhage (ICH) is a devastating neurological disease causing severe sensorimotor dysfunction and cognitive decline, yet there is no effective treatment strategy to alleviate outcomes of these p...

    **angyang Deng, Junwei Ren, Kezhu Chen, ** Zhang in Journal of Neuroinflammation (2024)

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    Article

    PAX2 mediated upregulation of ESPL1 contributes to cisplatin resistance in bladder cancer through activating the JAK2/STAT3 pathway

    Extra spindle-polar body like 1 (ESPL1) is associated with the development of a variety of cancers, including bladder cancer, and is closely related to chemoresistance. In this study, we aimed to reveal the ro...

    Wei Zhang, Yong Wang, Qisheng Tang in Naunyn-Schmiedeberg's Archives of Pharmaco… (2024)

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    Article

    Stereopure AIMer: A Promising RNA Base-editing Tool for Monogenic Neurological Diseases

    **gyu Yu, Tianwen Li, Kezhu Chen, Qisheng Tang, Jianhong Zhu in Neuroscience Bulletin (2023)

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    Article

    Effects of Compound 511 on BDNF-TrkB Signaling in the Mice Ventral Tegmental Area in Morphine-Induced Conditioned Place Preference

    Compound 511 (511) is specially developed for opioid addiction treatment based on the Ancient Chinese drug rehabilitation literature, and its composition has profound effects in the treatment of drug addiction...

    Han Zhang, Qisheng Wang, Qinmei Sun, Fenfen Qin in Cellular and Molecular Neurobiology (2021)

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    Article

    Crocin Reverses Depression-Like Behavior in Parkinson Disease Mice via VTA-mPFC Pathway

    Depression is a common non-motor symptom in patients with Parkinson’s disease (PD) and difficult to treat. Crocin is a natural multipotential neuroprotective compound that has been shown to elicit antidepressa...

    Juanjuan Tang, Linyu Lu, Qisheng Wang, Hou Liu, Wenda Xue in Molecular Neurobiology (2020)

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    Article

    The Tumorgenicity of Glioblastoma Cell Line U87MG Decreased During Serial In Vitro Passage

    Established cancer cell lines are routinely used to study cancer. Several factors such as serial passage may affect the reproducibility of experiments with cancer cell lines, but few researches focused on thes...

    Yu Zeng, **zhao Wang, Jizhou Wang, Renhui Yi in Cellular and Molecular Neurobiology (2018)

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    Current status of cell-mediated regenerative therapies for human spinal cord injury

    During the past decade, significant advances have been made in refinements for regenerative therapies following human spinal cord injury (SCI). Positive results have been achieved with different types of cells...

    Tongming Zhu, Qisheng Tang, Huasong Gao, Yiwen Shen, Lu** Chen in Neuroscience Bulletin (2014)

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    Hepatitis C virus infection activates an innate pathway involving IKK-α in lipogenesis and viral assembly

    Lipid droplets have a key role in the assembly of hepatitis C virus (HCV) particles in liver cells. Jake Liang and colleagues now report that a host factor, IκB kinase-α is required for efficient production of...

    Qisheng Li, Véronique Pène, Siddharth Krishnamurthy, Helen Cha in Nature Medicine (2013)

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    Biodegradable flow-diverting device for the treatment of intracranial aneurysm: short-term results of a rabbit experiment

    One main complication of a flow-diverting device (FD) in treating intracranial aneurysm is stenosis of parent artery (PA) or occlusion of side branches. The use of a biodegradable device may satisfy the need f...

    Kuizhong Wang, Shaoji Yuan, Xu** Zhang, Qiang Liu, Qisheng Zhong in Neuroradiology (2013)

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    Article

    Control of ecdysteroidogenesis: Activation and inhibition of prothoracic gland activity

    The ecdysteroid hormones, mainly 20-hydroxyecdysone (20E), play a pivotal role in insect development by controlling gene expression involved in molting and metamorphosis. In the model insectManduca sexta the prod...

    Lawrence I. Gilbert, Qisheng Song, Robert Rybczynski in Invertebrate Neuroscience (1997)