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Article
Open AccessCharacterization of the intestinal microbiota in MSM with HIV infection
HIV-infected persons demonstrate notable disturbances in their intestinal microbiota; however, the impact of intestinal microbiota on HIV susceptibility in men who have sex with men (MSM), as well as the effec...
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Article
Andrographolide and Its Derivative Potassium Dehydrographolide Succinate Suppress PRRSV Replication in Primary and Established Cells via Differential Mechanisms of Action
Porcine reproductive and respiratory syndrome virus (PRRSV) continues to cause significant economic loss worldwide and remains a serious threat to the pork industry. Currently, vaccination strategies provide l...
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Article
Antibiotic Resistance Characterization of Bacteria Isolated from Traditional Chinese Paocai
In this work, the antibiotic resistance of 218 isolates to 9 different antibiotics was analyzed with minimum inhibitory concentration method. All Lactobacillus pentosus strains were found to be resistant to strep...
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Article
Open AccessCharacterization of a novel Helitron family in insect genomes: insights into classification, evolution and horizontal transfer
Helitrons play an important role in sha** eukaryotic genomes due to their ability to transfer horizontally between distantly related species and capture gene fragments during the transposition. However, the mec...
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Article
Open AccessMicroRNA-135a Modulates Hepatitis C Virus Genome Replication through Downregulation of Host Antiviral Factors
Cellular microRNAs (miRNAs) have been shown to modulate HCV infection via directly acting on the viral genome or indirectly through targeting the virus-associated host factors. Recently we generated a comprehe...
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Article
Venom from the scorpion Heterometrus liangi inhibits HeLa cell proliferation by inducing p21 expression
Scorpion venoms are important sources for identifying and develo** promising biomolecules for cancer treatment. To search for promising biomolecules for cancer research, the effects of crude venom from the s...
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Article
Surface-displayed porcine reproductive and respiratory syndrome virus from cell culture onto gram-positive enhancer matrix particles
Vaccine immunization is now one of the most effective ways to control porcine reproductive and respiratory syndrome virus (PRRSV) infection. Impurity is one of the main factors affecting vaccine safety and eff...
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Article
Open AccessNICD-mediated notch transduction regulates the different fate of chicken primordial germ cells and spermatogonial stem cells
Notch signaling is mainly regulated by Notch1 during development of chicken germ stem cells; however, the molecular mechanisms that contribute to generation of these germ stem cells have not been thoroughly in...
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Article
The ectomycorrhizal fungal communities associated with Quercus liaotungensis in different habitats across northern China
Quercus liaotungensis is a major tree species in deciduous broad-leaved forests in northern China. In this study, we investigated ectomycorrhizal (ECM) communities associated with Q. liao...
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Article
Diversity and community structure of ectomycorrhizal fungi associated with Larix chinensis across the alpine treeline ecotone of Taibai Mountain
Alpine treeline ecotones represent ecosystems that are vulnerable to climate change. We investigated the ectomycorrhizal (ECM) community, which has potential to stabilize alpine ecosystems. ECM communities ass...
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Article
The Rab1 in host cells modulates Brucella intracellular survival and binds to Brucella DnaK protein
The intracellular pathogen Brucella abortus (B. abortus) survives and replicates inside host cells within the Brucella-containing vacuole, in which membrane contains a small GTPase Rab1. Here, we reported that Ra...
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Article
Open AccessMicroRNA-125b-5p suppresses Brucella abortus intracellular survival via control of A20 expression
Brucella may establish chronic infection by regulating the expression of miRNAs. However, the role of miRNAs in modulating the intracellular growth of Brucella remains unclear.
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Chapter and Conference Paper
Sumoylation of the Nucleocapsid Protein of Severe Acute Respiratory Syndrome Coronavirus by Interaction with UBC9