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  1. Article

    Open Access

    Integrated transcriptome and metabolome analysis reveals the molecular responses of Pardosa pseudoannulata to hypoxic environments

    Terrestrial organisms are likely to face hypoxic stress during natural disasters such as floods or landslides, which can lead to inevitable hypoxic conditions for those commonly residing within soil. Pardosa pseu...

    **** Li, Yun-e Tang, Bo Lv, Juan Wang, Zhi Wang, Qisheng Song in BMC Zoology (2024)

  2. Article

    Open Access

    Characterization of the intestinal microbiota in MSM with HIV infection

    HIV-infected persons demonstrate notable disturbances in their intestinal microbiota; however, the impact of intestinal microbiota on HIV susceptibility in men who have sex with men (MSM), as well as the effec...

    Yuansheng Fu, Susu Ke, Gan Tang, Qisheng Guo, Qian Guo, Ziwei Wang in BMC Microbiology (2024)

  3. No Access

    Article

    lncCPSET1 acts as a scaffold for MLL2/COMPASS to regulate Bmp4 and promote the formation of chicken primordial germ cells

    Primordial germ cells (PGCs) are the ancestors of female and male germ cells. Recent studies have shown that long non-coding RNA (lncRNA) and histone methylation are key epigenetic factors affecting PGC format...

    Ying Ding, Chen Zhang, Qisheng Zuo, Kai **, Bichun Li in Molecular Genetics and Genomics (2024)

  4. Article

    Open Access

    DDRGK1-mediated ER-phagy attenuates acute kidney injury through ER-stress and apoptosis

    Acute kidney injury (AKI) constitutes a prevalent clinical syndrome characterized by elevated morbidity and mortality rates, emerging as a significant public health issue. This study investigates the interplay...

    Haijiao **, Yuanting Yang, Xuying Zhu, Yin Zhou, Yao Xu, Jialin Li in Cell Death & Disease (2024)

  5. Article

    Open Access

    Map** the forage nitrogen, phosphorus, and potassium contents of alpine grasslands by integrating Sentinel-2 and Tiangong-2 data

    Nitrogen (N), phosphorus (P), and potassium (K) contents are crucial quality indicators for forage in alpine natural grasslands and are closely related to plant growth and reproduction. One of the greatest cha...

    Xuanfan Zhang, Tiangang Liang, **long Gao, Dongmei Zhang, Jie Liu in Plant Methods (2023)

  6. Article

    Open Access

    HIF1α-BNIP3-mediated mitophagy protects against renal fibrosis by decreasing ROS and inhibiting activation of the NLRP3 inflammasome

    Chronic kidney disease affects approximately 14.3% of people worldwide. Tubulointerstitial fibrosis is the final stage of almost all progressive CKD. To date, the pathogenesis of renal fibrosis remains unclear...

    Jialin Li, Qisheng Lin, **nghua Shao, Shu Li, Xuying Zhu in Cell Death & Disease (2023)

  7. No Access

    Article

    The urgent need to develop a new grassland map in China: based on the consistency and accuracy of ten land cover products

    Grasslands are the most dominant terrestrial ecosystem in China, but few national grassland maps have been generated. The grassland resource map produced in the 1980s is widely used as background data, but it ...

    Meng**g Hou, **g Ge, Yang**g **u, Bao** Meng, Jie Liu in Science China Life Sciences (2023)

  8. Article

    Open Access

    Isolation of Swine Bone Marrow Lin-/CD45-/CD133 + Cells and Cardio-protective Effects of its Exosomes

    The identification in murine bone marrow (BM) of CD133 + /Lin-/CD45- cells, possessing several features of pluripotent stem cells, encouraged us to investigate if similar population of cells could be also isol...

    Hongxiao Li, Jianjun Gu, **aolin Sun, Qisheng Zuo in Stem Cell Reviews and Reports (2023)

  9. No Access

    Article

    iTRAQ-Based Comparative Proteomic Analysis Provides Insights into Tobacco Callus Response to Carbon Nanoparticles

    Carbon nanomaterials (CNMs) have attracted a great deal of research interest for their potential application in plants. Some types of CNMs have exhibited the ability on regulating plant growth of plants, which...

    Zhenjie Zhao, Liwei Hu, Qiansi Chen, Huaxin Dai in Plant Molecular Biology Reporter (2022)

  10. Article

    Open Access

    The kinase activity of integrin-linked kinase regulates cellular senescence in gastric cancer

    The activity of integrin-linked kinase (ILK) in cancerous cells is often oncogenic and associated with malignant properties, such as uncontrolled cell cycle progression and evasion from senescence. However, th...

    Chengbo Ji, Mili Zhang, Junjie Hu, Can Cao, Qisheng Gu, Youdong Liu in Cell Death & Disease (2022)

  11. Article

    Open Access

    Structural insights into the SARS-CoV-2 Omicron RBD-ACE2 interaction

    Jun Lan, **nheng He, Yifei Ren, Ziyi Wang, Huan Zhou, Shilong Fan in Cell Research (2022)

  12. Article

    Open Access

    Genome of the parasitoid wasp Cotesia chilonis sheds light on amino acid resource exploitation

    A fundamental feature of parasitism is the nutritional exploitation of host organisms by their parasites. Parasitoid wasps lay eggs on arthropod hosts, exploiting them for nutrition to support larval developme...

    **nhai Ye, Shijiao **ong, Ziwen Teng, Yi Yang, Jiale Wang, Kaili Yu in BMC Biology (2022)

  13. No Access

    Article

    Characteristics of the TDRD1 gene promoter in chickens

    Tudor domain containing 1 (TDRD1) is a member of the TDRD family and plays an important role in embryogenesis and gametogenesis. A detailed study of the characteristics of chicken TDRD1 can lay a foundation fo...

    **aomin Gao, **aolin Sun, Pei Xu, **ang Shi, Ming Zhang in Molecular Genetics and Genomics (2022)

  14. No Access

    Chapter

    Sensor-Assisted Next-Generation Diagnostics: Emerging Concepts, Biomarkers, Technologies, and Challenges

    The evolution of medical diagnosis has continued to broaden our understanding of diseases. The development of various omics technologies and the continuous advancement of medical sensor technology are pushing ...

    Weiqiu **, Qisheng Yang, Shangjian Liu, Changzi Dong in Miniaturized Biosensing Devices (2022)

  15. No Access

    Chapter

    Biocompatible Sensors Are Revolutionizing Healthcare Technologies

    Sensors bridge the gap between disease diagnosis and the attainability of physiological indicators. The Internet of Things (IoT) and artificial intelligence algorithms have become the core of new-generation he...

    Qisheng Yang, Weiqiu **, Tian Lu, Shangjian Liu in Miniaturized Biosensing Devices (2022)

  16. No Access

    Article

    Antibiotic Resistance Characterization of Bacteria Isolated from Traditional Chinese Paocai

    In this work, the antibiotic resistance of 218 isolates to 9 different antibiotics was analyzed with minimum inhibitory concentration method. All Lactobacillus pentosus strains were found to be resistant to strep...

    Mei Li, Yao Tang, Liyan Guo, Tao Lei, Yunfei Deng, Liang Wang in Current Microbiology (2021)

  17. Article

    Open Access

    Screening of potent neutralizing antibodies against SARS-CoV-2 using convalescent patients-derived phage-display libraries

    As the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to threaten public health worldwide, the development of effective interventions is urgently needed. Neutralizing antibodies (nAbs) ...

    Yongbing Pan, Jianhui Du, Jia Liu, Hai Wu, Fang Gui, Nan Zhang in Cell Discovery (2021)

  18. Article

    Structure of SARS-CoV-2 main protease in the apo state

    Xuelan Zhou, Fanglin Zhong, Cheng Lin, **aohui Hu, Yan Zhang in Science China Life Sciences (2021)

  19. Article

    Open Access

    20E-mediated regulation of BmKr-h1 by BmKRP promotes oocyte maturation

    Krüppel homolog 1 (Kr-h1) is a critical transcription factor for juvenile hormone (JH) signaling, known to play a key role in regulating metamorphosis and adult reproduction in insects. Kr-h1 can also be induc...

    Zidan Zhu, Chunmei Tong, Binbin Qiu, Hongguang Yang, Jiahui Xu, Sichun Zheng in BMC Biology (2021)

  20. Article

    Open Access

    Genome-wide analysis of DNA G-quadruplex motifs across 37 species provides insights into G4 evolution

    G-quadruplex (G4) structures have been predicted in the genomes of many organisms and proven to play regulatory roles in diverse cellular activities. However, there is little information on the evolutionary hi...

    Feng Wu, Kangkang Niu, Yong Cui, Cencen Li, Mo Lyu, Yandong Ren in Communications Biology (2021)

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